From: Japanese encephalitis vaccine-facilitated dengue virus infection-enhancement antibody in adults
Sample no. (post-JE vaccination) (n = 35)c | Fold enhancement to DENVa | ADE activity to number of DENV serotypes | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
DENV-1 | DENV-2 | DENV-3 | DENV-4 | |||||||
Undiluted | 1:10-dilution | Undiluted | 1:10-dilution | Undiluted | 1:10-dilution | Undiluted | 1:10-dilution | Undiluted | 1:10-dilution | |
3 | –b | – | – | – | – | – | 3.1 | 2.5 | 1 | 1 |
9 | – | – | – | – | – | – | 2.2 | 1.9 | 0 | 1 |
11 | 4.5 a | 2.3 | 3.2 | 4.0 | 4.1 a | 2.9 | 2.3 | 2.7 | 3 | 4 |
13 | 13.0 | 2.8 | 4.0 | 2.8 | 5.9 | 2.1 | 4.5 | 2.8 | 4 | 3 |
19 | – | – | – | – | 4.4 | 2.6 | – | – | 1 | 1 |
202 | 14.5 | 2.6 | 2.8 | 3.6 | 5.3 | 2.5 | 3.3 | 2.4 | 4 | 4 |
211 | – | – | 4.2 | 2.6 | 4.3 | 3.5 | 4.9 | 2.8 | 3 | 3 |
22 | 3.5 | 2.0 | – | – | – | – | – | – | 1 | 1 |
313 | 2.5 | 3.0 | 6.6 | 4.8 | 2.7 | 3.2 | 4.7 | 2.4 | 2 | 4 |
321 | – | – | – | – | 2.5 | 2.5 | – | – | 0 | 1 |
33 | 6.0 | 2.5 | 2.5 | 3.8 | 4.1 | 3.9 | 4.4 | 2.2 | 4 | 4 |
43 | – | – | 5.1 | 2.8 | 4.9 | 4.8 | 6.6 | 1.8 | 3 | 2 |
47 | – | – | – | – | 3.2 | 3.3 | 1.6 | 2.3 | 0 | 2 |
49 | – | – | – | – | 3.9 | 2.3 | – | – | 1 | 1 |
512 | 6.7 | 2.6 | – | – | 5.0 | 2.6 | 3.3 | 2.3 | 3 | 3 |
53 | – | – | – | – | 3.9 | 2.0 | – | – | 1 | 1 |
54 | – | – | – | – | 5.0 | 3.5 | – | – | 1 | 1 |
573 | 6.7 | 2.2 | 5.5 | 2.0 | Â | Â | 4.5 | 2.7 | 3 | 3 |
58 | 4.0 | 1.9 | 1.5 | 3.2 | 4.1 | 3.2 | 3.4 | 3.8 | 3 | 3 |
593 | 4.3 | 4.2 | 1.2 | 2.5 | 4.0 | 3.9 | 1.0 | 3.4 | 2 | 4 |
61 | 7.3 | 2.1 | – | – | – | – | – | – | 1 | 1 |
732 | – | – | 0.4 | 2.3 | 4.1 | 3.5 | 1.3 | 3.5 | 1 | 3 |
77 | – | – | – | – | 6.3 | 4.0 | 3.3 | 1.8 | 2 | 1 |
781 | – | – | – | – | 2.0 | 2.2 | – | – | 0 | 1 |
79 | 2.0 | 2.2 | 1.1 | 3.6 | 5.0 | 6.7 | 3.8 | 2.7 | 2 | 4 |
80 | 4.0 | 2.1 | 2.5 | 2.5 | 5.4 | 3.2 | – | – | 3 | 3 |
85 | – | – | – | – | – | – | 6.2 | 2.6 | 1 | 1 |
861 | 1.7 | 2.4 | 1.0 | 3.3 | 2.9 | 4.6 | 2.3 | 2.5 | 0 | 4 |
893 | 7.0 | 4.1 | 4.2 | 2.0 | 4.8 | 5.1 | 3.3 | 3.3 | 4 | 4 |
93 | – | – | – | – | 3.1 | 3.2 | 1.9 | 2.4 | 0 | 2 |
941 | – | – | – | – | – | – | 5.8 | 2.6 | 1 | 1 |
951 | – | – | – | – | – | – | 2.1 | 2.1 | 0 | 1 |
961 | – | – | 4.0 | 2.0 | 3.8 | 3.1 | 3.8 | 5.2 | 3 | 3 |
100 | – | – | – | – | – | – | 2.4 | 2.1 | 0 | 1 |
110 | – | – | – | – | 4.9 | 2.8 | 3.4 | 2.2 | 2 | 2 |
Total number of samples | 12 | 14 | 11 | 16 | 20 | 24 | 17 | 24 | Â | Â |