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Table 1 Minimal inhibitory concentrations (MIC) of ertapenem susceptible carbapenemase producing isolates

From: Antimicrobial susceptibility testing in predicting the presence of carbapenemase genes in Enterobacteriaceae in South Africa

Sample ID ORGANISM NDM KPC OXA-48 & variants IMP VIM GES Cefepime MIC Cefotaxime MIC Ceftazidime MIC Ertapenem MIC Imipenem MIC Meropenem MIC Doripenem MIC
ML0148.2 Enterobacter cloacae - - - + - - >16 >32 >16 <=0.5 <=2 <=1 Not tested
ML0191 Klebsiella pneumoniae - - - - - + 8 >32 >16 <=0.5 <=2 <=1 Not tested
ML0440 Klebsiella pneumoniae - - - - + - 16 >32 >16 <=0.5 4 2 Not tested
ML0446 Klebsiella pneumoniae - - - - + - <=1 <=1 <=1 <=0.5 <=2 <=1 Not tested
ML0848 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 4 <=1 <=1
ML0917 Providencia rettgeri + - - - - - <=1 <=1 <=1 <=0.5 <=1 <=1 <=1
ML0926 Escherichia coli + - - - - - <=1 <=1 <=1 <=0.5 <=1 <=1 <=1
ML0930 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 4 <=1 <=1
ML1002 Providencia rettgeri + - - - - - 8 32 >16 <=0.5 >8 2 2
ML1007 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 4 <=1 2
ML1161 Klebsiella pneumoniae - - + - - - >16 >32 >16 <=0.5 <=2 <=1 Not tested
ML1187 Escherichia coli - - + - + - 2 8 16 <=0.5 4 <=1 <=1
ML1189 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 2 <=1 <=1
ML1219 Klebsiella pneumoniae - - - - + - 16 >32 >16 <=0.5 2 <=1 <=1
ML1279 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 2 <=1 <=1
ML1296 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 4 <=1 <=1
ML1340 Morganella morganii + - - - - - 8 >32 >16 <=0.5 8 <=1 2
ML1354 Klebsiella pneumoniae - - - - + - >16 >32 >16 <=0.5 4 <=1 2
  1. CLSI breakpoints: Cefepime: <=2 – Susceptible, 4-8 – Susceptible-Dose Dependant, > = 16 – Resistant; Cefotaxime: <=1 - Susceptible, 2 – Intermediate, > = 4 – Resistant; Ceftazidime: <=4 - - Susceptible, 8 – Intermediate, > = 16 – Resistant; Ertapenem: <=0.5- Susceptible, 1 – Intermediate, > = 2 – Resistant; Imipenem/Meropenem/Doripenem: <=1 – Susceptible, 2 – Intermediate, > = 4 Resistant [34]