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Table 1 Factors influencing malaria parasite prevalence and density in a paediatric HIV infected population in Cameroon
| Characteristic/category | Number examined | Number positive (%) | Bivariate analysis | Multivariate analysis | GMPD (range) | Statistic | P-value | ||
|---|---|---|---|---|---|---|---|---|---|
| OR (95 % CI) | P-value$ | OR (95 % CI) | P-value£ | ||||||
| Age Group (years) | |||||||||
| < 5 | 66 | 16 (24.2) | 1.67 (0.62–4.12) | 0.455 | 1.02 (0.28–3.71) | 0.976 | 633.0 (80–24000) | H = 3.406 | 0.18 |
| 5–10 | 120 | 34 (28.3) | 1.97 (0.84–4.67) | 0.167 | 3.05 (1.11–8,42) | 0.031* | 234.0 (40–24000) | ||
| 11–15 | 48 | 8 (16.7) | Reference | 463.3 (40–16000) | |||||
| Sex | |||||||||
| Males | 96 | 14 (14.6) | Reference | 549.0 (40–2400) | U = 218.0 | 0.10 | |||
| Females | 138 | 44 (31.9) | 2.74 (1.40–5.36) | 0.004* | 3.08 (1.37–6.93) | 0.007* | 290.0 (40–24000) | ||
| Fever | |||||||||
| Yes | 14 | 4 (28.6) | 1.23 (0.37–4.08) | 0.985 | 1.38 (0.24–7.88) | 0.716 | 3098.4 (400–24000) | U = 34.00 | 0.02* |
| No | 220 | 54 (24.5) | Reference | 287.3 (40–2400) | |||||
| CD4 T cell (cells/μl of blood) | |||||||||
| < 200 | 28 | 8 (28.6) | 1.20 (0.49–2.96) | 0.873 | 1.80 (0.55–5.85) | 0.33 | 82.4 (40–360) | H = 11.598 | 0.003* |
| 200–499 | 44 | 12 (27.3) | 1.07 (0.37–3.06) | 0.881 | 1.20 (0.46–3.13) | 0.70 | 405.2 (80–16000) | ||
| ≥ 500 | 144 | 36 (25.0) | Reference | 491.3 (40–24000) | |||||
| Clinical stages | |||||||||
| Stage 1 | 44 | 16 (36.4) | 4.29 (1.28–14.4) | 0,027* | 10.38 (2.43–44.46) | 0.0016* | 191.2 (40–5040) | H = 14.36 | 0.002* |
| Stage 2 | 62 | 10 (16.1) | 1.44 (0.42–5.00) | 0.782 | 1.46 (0.36–5.87) | 0.59 | 512.2 (40–5400) | ||
| Stage 3 | 82 | 24 (29.3) | 3.10 (0.99–9.77) | 0.077 | 2.62 (0.76–9.09) | 0.13 | 498.4 (80–2400) | ||
| Stage 4 | 34 | 4 (11.8) | Reference | 40.0 (40–40) | |||||
| Use of ART | |||||||||
| Yes | 182 | 52 (28.6) | Reference | 314.8 (40–24000) | U = 136.00 | 0.62 | |||
| No | 52 | 6 (11.5) | 3.07 (1.24–7.61) | 0.019* | 0.194 (0.06–0.62) | 0.0001* | 635.0 (40–16000) | ||
