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Table 6 Cox proportional hazards model predicting time to resolution of TB-IRIS symptoms excluding Brooklyn Chest Hospital cohort (Cohort 2)

From: Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors

  Adjusted HR (95 % CI) p-value
Age (per 1 year increase) 0.99 (0.96–1.01) 0.36
Male gender 1.42 (0.92–2.18) 0.11
Lymph node involvement at initial TB diagnosis 0.72 (0.44–1.17) 0.18
Drug-resistant TB 0.65 (0.36–1.20) 0.17
Hospitalised at time of TB-IRIS diagnosis 0.93 (0.62–1.40) 0.73
TB-IRIS pulmonary involvement 1.23 (0.82–1.83) 0.32
TB-IRIS lymph node involvement 0.60 (0.40–0.89) 0.01
  1. In the Cox proportional hazards model, even when the Brooklyn Chest Hospital cohort (Cohort 2) was excluded, TB-IRIS lymph node involvement remained statistically significantly associated with a lower hazard of TB-IRIS resolution (aHR 0.60, 95 % CI 0.40–0.89; p = 0.01)