From: Early diagnosis of dengue disease severity in a resource-limited Asian country
DHF/DSS | Severe Dengue | |||||||
---|---|---|---|---|---|---|---|---|
Se | Sp | PPVa | NPVb | Se | Sp | PPV | NPV | |
Warning Signs | ||||||||
Abdominal tenderness | 43.2 | 77.0 | 43.2 | 86.8 | 40.0 | 74.6 | 10.9 | 94.1 |
Persistent vomiting | 21.1 | 97.0 | 58.8 | 85.6 | 37.5 | 96.3 | 44.1 | 95.2 |
Clinical fluid accumulation | 66.3 | 96.1 | 77.8 | 93.3 | 90.0 | 91.3 | 44.4 | 99.2 |
Mucosal bleeding | 22.1 | 92.0 | 36.2 | 85.1 | 20.0 | 90.3 | 13.8 | 93.6 |
Lethargy/restlessness | 44.2 | 83.3 | 35.3 | 87.9 | 60.0 | 81.6 | 20.2 | 96.3 |
Liver enlargement > 2 cm | 55.8 | 82.0 | 39.0 | 90.0 | 65.0 | 78.7 | 19.1 | 96.7 |
Warning Signs Count | ||||||||
• at least one | 92.6 | 51.8 | 28.3 | 97.2 | 92.5 | 47.1 | 11.9 | 98.8 |
• at least two | 73.7 | 82.9 | 47.0 | 93.9 | 80.0 | 77.4 | 21.5 | 98.0 |
• at least three | 52.6 | 95.2 | 69.4 | 90.7 | 70.0 | 91.5 | 38.9 | 97.5 |
• at least four | 22.1 | 98.3 | 72.4 | 86.0 | 42.5 | 97.7 | 58.6 | 95.7 |
• at least five | 9.5 | 99.4 | 75.0 | 84.2 | 22.5 | 99.4 | 75.0 | 94.3 |
• All six are present | 2.1 | 100.0 | 100.0 | 83.2 | 7.2 | 100.0 | 100.0 | 93.2 |