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Table 2 Susceptibilities of MDR M. tuberculosis isolates of 2009 to fluoroquinolonesa

From: Persistently high prevalence of primary resistance and multidrug resistance of tuberculosis in Heilongjiang Province, China

MIC (mg/L) Levofloxacin Moxifloxacin Sparfloxacin Gemifloxacin Gatifloxacin
No. % No. % No. % No. % No. %
≤0.125        2 3.8 1 1.9
≤0.25 7 13.4 5 9.6 14 26.9 7 13.5 8 15.4
0.50 10 19.2 18 34.6 9 17.3 14 26.9 15 28.8
1 mg/L 15 28.8 15 28.8 10 19.2 9 17.3 7 13.5
2.00 8 15.4 9 17.3 8 15.4 14 26.9 12 23.1
4.00 8 15.4 3 5.8 7 13.5 6 11.5 7 13.5
8.00 4 7.7 2 3.8 3 5.8    2 3.8
16.00      1 1.9     
MIC ≥ 2 mg/L 20 38.5 14 26.9 19 36.5 20 38.4 21 40.4
MIC50b 1.0   1.0   1.0   1.0   1.0  
  1. a MDR multidrug resistance, MIC minimum inhibitory concentration
  2. bMIC50, minimum inhibitory concentration required to inhibit the growth of 50 % of examining clinical isolates