Persistently high prevalence of primary resistance and multidrug resistance of tuberculosis in Heilongjiang Province, China

Table 1 Susceptibility of the M .tuberculosis isolated in Heilongjiang Province to the first-line anti-tuberculosis drugs

Characteristics	2007		2008		2009		2010		2011		2012		Total
Characteristics	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
All	198		348		275		204		205		197		1427
Any drug resistance	110	55.6	209	60.1	189	68.7	121	59.3	89	43.4	96	48.7	814	57.0
RPF or INH^a,b	42	21.2	77	22.1	72	26.2	55	27.0	42	20.5	40	20.3	328	23.0
SM	72	36.4	152	43.7	125	45.5	86	42.2	63	30.7	63	32.0	561	39.3
EMB	47	23.7	74	21.3	75	27.3	16	7.8	17	8.3	18	9.1	247	17.3
MDR	44	22.2	90	25.9	81	29.5	39	19.1	33	16.1	38	19.3	325	22.8
Pan-resistance^c	21	10.6	49	14.1	37	13.5	10	4.9	12	5.9	11	5.6	140	9.8
From new cases	126		218		171		143		136		124		918
Any drug resistance	62	49.2	113	51.8	103	60.2	74	51.7	46	33.8	49	39.5	447	48.7
RPF or INH	24	19.0	43	19.7	46	26.9	37	25.9	24	17.6	23	18.5	197	21.5
SM	42	33.3	84	38.5	67	39.2	53	37.1	32	23.5	31	25.0	309	33.7
EMB	19	15.1	32	14.7	38	22.2	9	6.3	6	4.4	5	4.0	109	11.9
MDR	20	15.9	36	16.5	29	17.0	18	12.6	11	8.1	11	8.9	125	13.6
Pan-resistance	5	4.0	17	7.8	14	8.2	4	2.8	4	2.9	2	1.6	46	5.0
From re-treated cases	72		130		104		61		69		73		509
Any drug resistance	48	66.7	96	73.8	86	82.7	47	77.0	43	62.3	47	64.4	367	72.1
RPF or INH	18	25.0	34	26.2	26	25.0	18	29.5	18	26.1	17	23.3	131	25.7
SM	30	41.7	68	52.3	58	55.8	33	54.1	31	44.9	32	43.8	252	49.5
EMB	28	38.9	42	32.3	37	35.6	7	11.5	11	15.9	13	17.8	138	27.1
MDR	24	33.3	54	41.5	52	50.0	21	34.4	22	31.9	27	37.0	200	39.3
Pan-resistance	16	22.2	32	24.6	23	22.1	6	9.8	8	11.6	9	12.3	94	18.5

^a INH isoniazid, RFP rifampicin, MDR multidrug-resistance, SM streptomycin, EMB ethambutol
^bThe isolates were resistant to RPF or INH but not both
^cThe isolates were resistant to all the four first-line drug

ISSN: 1471-2334