Association of vitamin D deficiency with hepatitis B virus - related liver diseases

BMC Infectious Diseases

Table 4 Univariate and multivariate logistic regression analyses of factors associated with vitamin D deficiency

Variables	Univariate analysis		Multivariate analysis
Variables	OR (95 % CI)	P value	OR (95 % CI)	P value
HBV versus non-HBV (or HC) ^†	1.2 (0.7–2.0)	0.49	10.8 (1.4–81.8)	0.021
HCC versus non-HCC ^‡	2.4 (1.1–5.0)	0.029	2.4 (0.3–21.6)	0.43
Cirrhosis versus non-cirrhosis ^β	1.4 (0.8–2.5)	0.23	1.2 (0.5–2.7)	0.74
HBeAg (negative versus positive) ^γ	3.6 (1.2–10.7)	0.015	3.8 (1.2–12.0)	0.024

Univariate and multivariate logistic regression model for independent risk factors were applied. Independent risk factors added into the multivariate logistic regression model are age, gender, HCC status, cirrhosis status and HBeAg status. (†), 395 HBV cases vs. 120 HC; (‡), 105 HCC cases vs. 290 non-HCC HBV patients; (β), 127 LC patients vs. 268 non-cirrhosis HBV patients; (γ), 266 HBeAg negative vs. 129 HBeAg positive patients. HBV hepatitis B virus, HC healthy control, HBeAg Hepatitis B envelope antigen, HCC hepatocellular carcinoma

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