Table 1 Characteristics of the study cohort
From: Association of vitamin D deficiency with hepatitis B virus - related liver diseases
Characteristics | CHB (n = 165) | LC (n = 127) | HCC (n = 108) | HC (n = 122) | P value |
|---|---|---|---|---|---|
Age (median, range) | 39 (18–79) | 55 (19–84) | 55 (18–81) | 40 (19–58) | <0.001 |
Gender (male/female) | 135/30 | 107/20 | 99/9 | 82/40 | <0.001 |
Liver cirrhosis stage: | |||||
 Child-Pugh A (n, %) | NA | 42 (33.0 %) | NA | NA | NA |
 Child-Pugh B (n, %) | NA | 62 (48.8 %) | NA | NA | NA |
 Child-Pugh C (n, %) | NA | 23 (18.2 %) | NA | NA | NA |
WBC (×103/ml) | 6.5 (3.6–13.9) | 6.1 (1.8–20.5) | 5.2 (2.1–15.1) | NA | 0.007 |
RBC (×106/ml) | 4.9 (2.5–6.6) | 3.6 (1.9–6.4) | 4.2 (2.4–7.2) | NA | <0.001 |
PLT (×103/ml) | 197.5 (21.5–472) | 76.5 (24.4–641) | 161 (6.7–428) | NA | <0.001 |
AST (IU/L) | 100 (14–7700) | 93 (26–1221) | 53 (18–653) | NA | 0.014 |
ALT (IU/L) | 120 (9–4908) | 51.5 (8–1000) | 43 (4–401) | NA | <0.001 |
Total-Bilirubin (mg/dl) | 15.3 (6–499) | 35.5 (6.4–733) | 18 (9–185) | NA | <0.01 |
Direct-Bilirubin (mg/dl) | 4.5 (1–300) | 14.7 (1.6–449) | 5.6 (1.1–156) | NA | <0.01 |
Albumin (g/L) | 42 (16–53) | 30 (16–54) | 39.4 (22–47) | NA | <0.001 |
Prothrombin (%) | 89 (41–140) | 53.5 (14–101) | 77.8 (20–127) | NA | <0.001 |
HBV-DNA (log10 copies/ml) | 5.6 (2.4–10.1) | NA | NA | NA | NA |
Alpha fetoprotein (IU/L) | 2.7 (1.6–320) | 9.2 (1.5–300) | 196 (1.3–400) | NA | <0.001 |