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Table 1 Characteristics of the study cohort

From: Association of vitamin D deficiency with hepatitis B virus - related liver diseases

Characteristics CHB (n = 165) LC (n = 127) HCC (n = 108) HC (n = 122) P value
Age (median, range) 39 (18–79) 55 (19–84) 55 (18–81) 40 (19–58) <0.001
Gender (male/female) 135/30 107/20 99/9 82/40 <0.001
Liver cirrhosis stage:
 Child-Pugh A (n, %) NA 42 (33.0 %) NA NA NA
 Child-Pugh B (n, %) NA 62 (48.8 %) NA NA NA
 Child-Pugh C (n, %) NA 23 (18.2 %) NA NA NA
WBC (×103/ml) 6.5 (3.6–13.9) 6.1 (1.8–20.5) 5.2 (2.1–15.1) NA 0.007
RBC (×106/ml) 4.9 (2.5–6.6) 3.6 (1.9–6.4) 4.2 (2.4–7.2) NA <0.001
PLT (×103/ml) 197.5 (21.5–472) 76.5 (24.4–641) 161 (6.7–428) NA <0.001
AST (IU/L) 100 (14–7700) 93 (26–1221) 53 (18–653) NA 0.014
ALT (IU/L) 120 (9–4908) 51.5 (8–1000) 43 (4–401) NA <0.001
Total-Bilirubin (mg/dl) 15.3 (6–499) 35.5 (6.4–733) 18 (9–185) NA <0.01
Direct-Bilirubin (mg/dl) 4.5 (1–300) 14.7 (1.6–449) 5.6 (1.1–156) NA <0.01
Albumin (g/L) 42 (16–53) 30 (16–54) 39.4 (22–47) NA <0.001
Prothrombin (%) 89 (41–140) 53.5 (14–101) 77.8 (20–127) NA <0.001
HBV-DNA (log10 copies/ml) 5.6 (2.4–10.1) NA NA NA NA
Alpha fetoprotein (IU/L) 2.7 (1.6–320) 9.2 (1.5–300) 196 (1.3–400) NA <0.001
  1. Abbreviation: CHB chronic hepatitis B, LC liver cirrhosis, HCC hepatocellular carcinoma, HC healthy control, WBC white blood cells, RBC red blood cells, PLT platelets. AST and ALT aspartate and alanine amino transferase, IU international unit, NA not applicable. Values given are medians and range. P values were calculated by Chi-square test and Kruskal-Wallis test where appropriate