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Table 1 Slum (aglomerados subnormais - AGSN) and non-slum (non-AGSN) tuberculosis clinical and treatment characteristics, Rio de Janeiro, Brazil, 2010

From: Risk factors for differential outcome following directly observed treatment (DOT) of slum and non-slum tuberculosis patients: a retrospective cohort study

 

Total n (%)

Slum n (%)

Non-slum n (%)

P-value*

Number of cases

6601 (100.0)

1807 (27.4)

4794 (72.6)

-

Median age (IQR)

37 (26, 50)

38 (37, 51)

33 (23, 47)

-

Sex (% female)

2317 (35.1)

1666 (34.8)

651 (36.0)

0.313

Site of TB

 Pulmonary

5412 (82.0)

1515 (83.8)

3897 (81.3)

0.02

 Extrapulmonary

867 (13.1)

218 (12.1)

649 (13.5)

0.11

 Pulmonary and extrapulmonary

322 (4.9)

74 (4.1)

248 (5.2)

0.07

Case category

 New case

5173 (78.4)

1362 (75.4)

3811 (79.5)

<0.001

 Relapse after previous treatment completion

483 (7.3)

167 (9.2)

316 (6.6)

<0.001

 Relapse after loss to follow-up in previous treatment

545 (8.3)

177 (9.8)

368 (7.7)

0.01

 Unknown

73 (1.1)

16 (0.89)

57 (1.2)

0.29

 Transfer to other municipality

327 (5.0)

85 (4.7)

242 (5.1)

0.57

Tuberculin skin test result

 Not reactive (0-4 mm)

266 (4.0)

57 (3.2)

209 (4.4)

0.03

 Weak reaction (5-9 mm)

101 (1.5)

33 (1.8)

68 (1.4)

0.23

 Strong reaction (≥10 mm)

638 (9.7)

175 (9.7)

463 (9.7)

0.97

 Not performed

5590 (84.7)

1542 (85.3)

4048 (84.4)

0.37

Acid-fast bacilli smear at diagnosis

 Positive

3228 (48.9)

959 (53.1)

2269 (47.3)

<0.01§

 Negative

1551 (23.5)

368 (20.4)

1183 (24.7)

 

 Not performed

1822 (27.6)

480 (26.6)

1342 (28.0)

 

Indicated for DOT at diagnosis

 Yes; completed full course

1892 (28.7)

636 (35.2)

1256 (26.2)

<0.01

 Yes; did not complete full course

10 (0.2)

10 (0.6)

-

 

 No

4410 (66.8)

1081 (59.8)

3329 (69.4)

 

 Unknown

289 (4.4)

80 (4.4)

209 (4.4)

 

Treatment changed due to intolerance or failure

 Yes

45 (0.7)

17 (0.9)

28 (0.6)

0.12

 No/not recorded

6556 (99.3)

1709 (99.1)

4766 (99.4)

 

All contacts indicated at diagnosis examined at follow-up

 Yes

3349 (51.2)

855 (47.8)

2494 (52.5)

<0.01

 No

3195 (48.8)

935 (52.2)

2260 (47.5)

 

Median days (IQR) from diagnosis until notification

0 (0, 14)

0 (0, 14)

1 (0, 14)

-

Median days (IQR) from diagnosis until initiation of treatment

0 (0,0)

0 (0, 0)

0 (0, 1)

-

Median days (IQR) from initiation of treatment until change of treatment due to adverse reaction

175 (77, 238)

182 (79.5, 237.5)

149 (76, 244)

-

Median days (IQR) from diagnosis until end of follow-up

187 (145, 219)

187 (146, 218)

189 (145, 221)

-

  1. IQR interquartile range, 25th and 75th percentile
  2. * P-value calculated to compare selected characteristics between cases in slums versus and non-slums
  3. §Comparing positive versus negative AFB smear diagnosis
  4. Comparing all those assigned to DOT (regardless of completion)