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Table 5 Yield of HBsAg-/HBV DNA+ in blood donorsa

From: Prevalence of hepatitis B surface antigen (HBsAg) in a blood donor population born prior to and after implementation of universal HBV vaccination in Shenzhen, China

Category OBI WPI Unclassified Overall
Samples 106 11 27 144
Yield 1/4486 1/43,231 1/17,613 1/3302
Gender (F/M) 29/77 5/6 7/20 41/103
Age range (median) 20–56 (34) 19–42 (28) 19–54 (28.5) 19–56 (32)
VL range (median, IU/ml) 0–2122 (23.1) 0–7321 (190.4) 0–2782 (36.4) 0–7321 (27.9)
Anti-HBc+/anti-HBs+/anti-HBe + (%) 2 0 0 2
Anti-HBc+/anti-HBs + (%) 34 0 0 34
Anti-HBc+/anti-HBe + (%) 4 3 0 7
Anti-HBc + only (%) 54 1 0 55
Anti-HBs + only (%) 8 0 0 8
HBeAg + only (%) 0 1 0 1
Anti-HBe + only (%) 0 0 0 0
No seromarker (%) 4 (primary OBI) 6 27 37
  1. aHBV DNA was detected by the NAT from 475,538 blood donors with negative HBsAg and normal ALT level (<50U/L). HBV DNA+/HBsAg- carriers were detected 1–3 times for HBV DNA and sero-markers by the follow-up. The blood samples were detected for HBV DNA+/HBsAg- in follow-up samples were defined as OBIs, for seroconversion of HBsAg were defined as window period infections (WPIs), while no available of follow-up testing were defined as unclassified that might include false positive of HBV DNA samples