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Table 1 Characteristics of all PCP cases (n = 743)

From: Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: a systematic review and meta-analysis

Age (years, mean) 35 (10 studies, n = 240)
Male sex (%) 39.6 (15 studies, n = 315)
CD4 count (cells/microL, median, IQR) 48 [31.5–129.0] (16 studies, n = 353)
Cotrimoxazole prophylaxis (%, 95 % CI) 5.9 [3.3–9.5] (11 studies, n = 255)
ART (%, 95 % CI) 0.4 [0.01–2.6] (11 studies, n = 215)
Co-existent opportunistic disease (%, 95 % CI)
 - Overall 29.3 [25.4–33.6] (26 studies, n = 474)
 - Tuberculosis 14.8 [11.8–18.5] (25 studies, n = 431)
 - Bacterial pneumonia 8.7 [0.6–11.8] (22 studies, n = 445)
 - Pulmonary cryptococcosis 1.4 [0.4–3.6] (17 studies, n = 283)
 - Pulmonary Kaposi sarcoma 4.1 [2.4–6.6] (21 studies, n = 410)
 - Pulmonary CMV 3.9 [1.4–8.2] (11 studies, n = 155)
 - Pulmonary MAC 0.8 [0.1–2.8] (19 studies, n = 254)
Case fatality rate (%, 95 % CI) 18.8 % [11.0–26.5] (12 studies, n = 334)
  1. IQR interquartile range; CI confidence interval; ART antiretroviral therapy; CMV cytomegalovirus; MAC mycobacterium avium complex