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Table 2 Joinpoint regression analysis of epidemiological indicators related to leprosy, 2001–2012

From: Trends of main indicators of leprosy in Brazilian municipalities with high risk of leprosy transmission, 2001–2012

Indicator State Annual percentage change (APC) Average annual percentage change (AAPC)
Period APC 95 % CI Intire period AAPC 95 % CI
Incidence rates of leprosy per 100,000 inhabitants Aggregated of municipalities 2001–2003 5.8 −5.3 a 18.1 2001–2012 −4.2* −5.9 a −2.4
2003–2012 −6.2* −7.2 a −5.2    
Rondônia 2001–2004 4.7 −4.7 a 14.9 2001–2012 −4.1* −6.5 a −1.7
2004–2012 −7.2* −9.3 a −5.1    
Pará 2001–2003 5.2 −13.1 a 27.3 2001–2012 −5.3* −8.3 a −2.3
2003–2012 −7.5* −9.3 a −5.8    
Tocantins 2001–2008 0.6 −1.9 a 3.1 2001–2012 −3.3* −5.5 a −1.1
2008–2012 −9.7* −15.2 a −4.0    
Maranhão 2001–2004 4.5 −5.0 a 15.0 2001–2012 −3.4* −5.8 a −1.0
2004–2012 −6.3* −8.3 a −4.2    
Mato Grosso 2001–2012 −5.2* −6.2 a −4.3 2001–2012 −5.2* −6.2 a −4.3
Other states of Brazil 2001–2003 6.3 −1.4 a 14.6 2001–2012 −4.0* −5.2 a −2.8
2003–2012 −6.2* −6.9 a −5.5    
Incidence rates of leprosy in children <15 years per 100,000 inhabitants Aggregated of municipalities 2001–2003 6.0 −10.1 a 24.9 2001–2012 −3.6* −6.2 a −1.0
2003–2012 −5.6* −7.2 a −4.1    
Rondônia 2001–2012 −3.0 −7.5 a 1.7 2001–2012 −3.0 −7.5 a 1.7
Pará 2001–2012 −5.3* −6.9 a −3.7 2001–2012 −5.3* −6.9 a −3.7
Tocantins 2001–2012 −0.9 −4.0 a 2.3 2001–2012 −0.9 −4.0 a 2.3
Maranhão 2001–2012 −3.5* −5.6 a −1.4 2001–2012 −3.5* −5.6 a −1.4
Mato Grosso 2001–2012 −5.9* −7.8 a −3.9 2001–2012 −5.9* −7.8 a −3.9
Other states of Brazil 2001–2003 7.9 −1.7 a 18.5 2001–2012 −2.7* −4.2 a −1.2
2003–2012 −4.9* −5.8 a 4.0    
Rates of new cases with grade-2 disabilities per 100,000 inhabitants Aggregated of municipalities 2001–2012 −1.3 −2.6 a 0.1 2001–2012 −1.3 −2.6 a 0.1
Rondônia 2001–2003 52.1 −33.8 a 249.0 2001–2012 0.9 −11.3 a 14.8
2003–2012 −7.8* −13.9 a −1.4    
Pará 2001–2012 −2.2 −4.4 a 0.1 2001–2012 −2.2 −4.4 a 0.1
Tocantins 2001–2012 −0.4 −3.0 a 2.2 2001–2012 −0.4 −3.0 a 2.2
Maranhão 2001–2004 −0.4 −2.8 a 2.1 2001–2012 −0.4 −2.8 a 2.1
Mato Grosso 2001–2012 −0.3 −2.7 a 1.9 2001–2012 −0.3 −2.7 a 1.9
Other states of Brazil 2001–2008 0.2 −2.0 a 2.5 2001–2012 −2.6* −4.3 a −0.9
2008–2012 −7.4* −11.3 a −3.2    
  1. *Significantly different from 0 (p <0.05)
  2. 95 % CI: 95 % confidence intervals