Utility of modified Faine’s criteria in diagnosis of leptospirosis

BMC Infectious Diseases

Table 2 Comparison of clinical features among clinically suspected leptospirosis patients; with confirmed and without a confirmed diagnosis based on MAT and /or PCR

Clinical features	Percentage of patients with confirmed diagnosis of leptospirosis^a (n = 66)	Percentage of patients without a confirmed diagnosis of leptospirosis^b (n = 102)	p value
Fever	100	100	-
Headache	72.7	73.5	0.909
Myalgia	81.8	85.3	0.549
Muscle tenderness	45.5	35.3	0.118
Vomiting	54.5	44.1	0.186
Conjunctivitis	19.7	11.8	0.158
Icterus	33.3	8.8	0.000*
Conjunctival haemorrhage	25.8	14.7	0.075
Meningitis	15.2	7.8	0.135
Dyspnoea	15.2	8.8	0.206
Albuminuria/nitrogen retention	68.2	50	0.020**

^a Confirmed diagnosis of leptospirosis included patients having symptoms consistent with leptospirosis and a single MAT titre ≥ 1:400; and / or Leptospira DNA detected by a method based on the polymerase chain reaction (PCR)
^b Patients negative for MAT and / or PCR (This includes presumptive and unconfirmed cases)
* p <0.001, **p < 0.05

ISSN: 1471-2334