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Table 6 Total cost of CDI management in US

From: Cost of hospital management of Clostridium difficile infection in United States—a meta-analysis and modelling study

Total number of HCF CDI cases per year (2011) [25] Mean 95 % CI
All population ≥2 years Median 293,300 264,200 322,500
 Adults ≥18 Upper boundary 288,900 261,100 316,700
 Adults ≥18 Lower boundary 133,887 91,780 195,402
Cost per CDI case management (2015 US$) Weighted Mean 90 % CI
 Overall CDI-attributable cost 21,448 21,152 21,744
 Overall CDI-related cost 42,316 39,886 44,765
Total cost per year (in Billions, 2015 US$) Weighted Mean Range
Total CDI-attributable cost per year 6.29 1.94 7.01
Mean 6.29 5.59 7.01
 Upper boundary 6.19 5.52 6.88
 Lower boundary 2.87 1.94 4.25
Total CDI-related cost per year 12.41 3.66 14.44
Mean 12.41 5.59 14.44
 Upper boundary 12.25 10.41 14.18
 Lower boundary 5.67 3.66 8.75
  1. Abbreviations: HCF healthcare facility, CDI clostridium difficile infection, CI confidence intervals