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Table 3 Multivariate logistic regression model of variables associated with poor pyrosequencing technical performance

From: Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis

Variable

Crude OR

95 % CI

Adjusted OR

95 % CI

AFB Smear

 Negative

5.30

4.76–5.90

2.19

1.91–2.51

 Positive

1.00

 

1.00

 

Culture

 Negative

8.44

7.51–9.49

7.74

6.67–8.99

 Positive

1.00

 

1.00

 

Site

 Moldova

2.07

1.84–2.34

2.86

2.47–3.31

 South Africa

1.86

1.64–2.10

1.50

1.29–1.74

 India

1.00

 

1.00

 

Target

 katG

1.52

1.19–1.92

1.69

1.29–2.21

 inhA

1.30

1.02–1.66

1.38

1.05–1.81

 ahpC

1.71

1.35–2.16

1.96

1.50–2.55

 rpoB1

3.65

2.93–4.55

5.29

4.12–6.79

 rpoB2

3.31

2.65–4.12

4.65

3.62–5.97

 gyrA

2.99

2.39–3.73

4.07

3.16–5.23

 rrs

1.90

1.50–2.39

2.24

1.72–2.91

 IS6110

1.00

 

1.00

 
  1. p < 0.01 for all bolded estimates except inhA (p < 0.05)