Table 2 Comparison of immunogenicity of 2010-2011 influenza vaccines against H1N1 pdm09 between infection-primed group and vaccine-primed group in children 9-18 years of age
IP (n = 32) | VP (n = 145) | P value | ||
|---|---|---|---|---|
Split/subunit ratio | 17/15 | 57/88 | 0.152 | |
Mean age | 12.57 (±2.52) | 12.22 (±2.22) | 0.432 | |
Seroprotection (%) | Baseline | 71.88 (23/32) | 57.24 (83/145) | 0.098 |
1 month | 93.75 (30/32) | 73.79 (107/145) | 0.001 | |
6 months | 78.26 (18/23) | 57.03 (73/128) | 0.038 | |
Seroconversion (%) | 68.75 (22/32) | 37.24 (54/145) | 0.001 | |
GMT (95 % CI) | Baseline | 45.55 (36.80–54.29) | 29.18 (25.51–32.84) | 0.041 |
1 month | 246.75 (177.61–315.89) | 69.98 (59.69–80.26) | 0.000 | |
6 months | 101.81 (65.66–137.96) | 39.57 (34.91–44.22) | 0.001 | |