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Table 1 Summary of M. tuberculosis susceptibility profile test based on Genotype MTBDRplus compared to gender, HIV co-infection and previous use of first line drugs against tuberculosis

From: Drug-resistant tuberculosis in Central Mozambique: the role of a rapid genotypic susceptibility testing

 

Gender

HIV

Previous treatment of TB

Total

M. tb status

M

F

Unk

p value

Pos

Neg

Unk

p value

Yes

No

Unk

p value

Susceptible

55 71.4 %

49 79.0 %

11 (68.7)

0,33

29 66.0 %

20 71.4 %

66 79.6 %

0,80

73 72.2 %

33 80.5 %

9 69.2 %

0,02

115 74.2 %

MDR-TB

12 15.6 %

10 16.2 %

3 (18.8)

11 25.0 %

5 17.9 %

9 (10.8)

20 19.8 %

4 9.8 %

1 7.7 %

25 16.1 %

R-mono resistant

2 2.6 %

0

0 (0.0)

1 2.2 %

0

1 1.2 %

1 1.0 %

1 2.4 %

0

2 1.3 %

H-mono resistant

8 10.4 %

3 4.8 %

2 (12.5)

3 6.8 %

3 10.7 %

7 8.4 %

7 7.0 %

3 7.3 %

3 23.1 %

13 8.4 %

Total

77

62

16

 

44

28

83

 

101

41

13

 

155 100 %

  1. M. tb Mycobacterium tuberculosis, M male, F female, Unk unknown, Pos positive, Neg negative, MDR-TB isolates resistant to rifampicin and isoniazid, R-mono resistant only to rifampicin, H-mono resistant only to isoniazid
  2. Chi-square and Fisher comparing susceptible and non-susceptible groups. Significance p < 0.05