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Table 4 In-hospital management of the 216 included patients, and comparison according to the consumption of anti-inflammatory drugs prior to admission

From: Impact of anti-inflammatory drug consumption in peritonsillar abscesses: a retrospective cohort study

 

Total population

No AID

AID

AID vs. no AID

NSAID

NAID vs. no AIDa

CT

Corticosteroids vs. no AIDa

NSAID vs. corticosteroidsa

p-value

p-value

p-value

p-value

n

216

89 (41.2 %)

127 (58.7 %)

 

76 (35.2 %)

 

67 (31.0 %)

  

Paraclinical tests

 CT-scan

77 (35.6 %)

38 (42.7 %)

39 (30.7 %)

0.070

23 (30.3 %)

0.305

19 (28.4 %)

0.185

0.842

  Abscess volume (cm3)

4.4 (1.6–10.2)

2.9 (0.9–7.8)

6.8 (3.7–12.7)

0.005

5.7 (3.2–10.6)

0.028

7.1 (1.9–13.5)

0.049

0.728

 CRP (mg/L)

90.0 (44.4–156.5)

109.5 (66.9–172.8)

72.4 (38.3–133.0)

0.002

95.1 (50.9–181.0)

0.663

47.5 (26.5–81.5)

<10−3

<10−3

 WBC (/mm3)

14,400 (12,100–17,700)

13,500 (12,000–16,200)

15,400 (12,50–18,300)

0.031

15,600 (12,600–17,700)

0.131

15,500 (12,500–19,100)

0.111

0.605

 Neutrophils (/mm3)

13,600 (10,100–16,200)

12,800 (9400–15,600)

14,100 (10,400–16,500)

0.326

14,200 (11,300–15,600)

0.437

14,100 (10,300–17,000)

0.454

0.927

Hospitalisation

215 (99.5 %)

88 (98.9 %)

127 (100.0 %)

0.412

76 (100.0 %)

1.000

67 (100.0 %)

1.000

NC

 Hospital stay (d)

3.0 (3.0–4.0)

3.0 (3.0–4.0)

3.0 (3.0–4.0)

0.170

3.0 (3.0–4.0)

0.492

3.0 (3.0–4.0)

0.066

0.344

 ICU

3 (1.4 %)

1 (1.1 %)

2 (1.6 %)

1.000

2 (2.6 %)

0.565

0 (0.0 %)

1.000

0.499

Surgical management

203 (94 %)

83 (93.3 %)

120 (94.5 %)

0.708

73 (96.1 %)

0.740

63 (94 %)

1.000

0.539

 Puncture/Incision

199 (92.1 %)

82 (92.1 %)

117 (92.1 %)

0.998

71 (93.4 %)

0.918

62 (92.5 %)

0.693

0.787

 Productive puncture

152 (70.4 %)

56 (62.9 %)

96 (75.6 %)

0.045

58 (76.3 %)

0.268

53 (79.1 %)

0.160

0.831

  Initial

199 (92.1 %)

82 (92.1 %)

117 (92.1 %)

0.998

71 (93.4 %)

0.918

62 (92.5 %)

0.758

0.787

  Secondary

80 (37 %)

34 (38.2 %)

46 (36.2 %)

0.767

31 (40.8 %)

0.849

24 (35.8)

0.294

0.419

 Surgery under GA

21 (9.7 %)

9 (10.1 %)

12 (9.4 %)

0.871

10 (13.2 %)

0.982

6 (9.0 %)

0.328

0.217

  Initial

5 (2.3 %)

1 (1.1 %)

4 (3.1 %)

0.330

3 (3.9 %)

0.346

2 (3.0 %)

1.000

1.000

  Secondary

18 (8.3 %)

8 (9.0 %)

10 (7.9 %)

0.806

9 (11.8 %)

0.836

4 (6.0 %)

0.155

0.122

  Cervicotomy

2 (0.9 %)

0 (0.0 %)

2 (1.6 %)

0.513

2 (2.6 %)

0.161

0 (0.0 %)

NC

0.499

  Tonsillectomy

12 (5.6 %)

4 (4.5 %)

8 (6.3 %)

0.765

7 (9.2 %)

0.715

4 (6.0 %)

0.653

0.372

 Iterative procedure

93 (43.1 %)

39 (43.8 %)

54 (42.5 %)

0.849

38 (50.0 %)

0.887

27 (40.3 %)

0.147

0.142

Medical management

 IV antimicrobial therapy

214 (99.1 %)

88 (98.9 %)

126 (99.2 %)

1.000

75 (98.7 %)

0.410

66 (98.5 %)

1.000

NC

 Total duration (d)

12.5 (11.0–15.0)

12.0 (11.0–15.0)

13.0 (10.0–16.0)

0.249

12.0 (10.0–15.3)

0.203

14.0 (12.0–17.5)

0.046

0.007

 From hospital admission (d)

10.0 (10.0–11.0)

10.0 (10.0–12.0)

10.0 (10.0–11.0)

0.021

10.0 (10.0–11.0)

0.204

10.0 (10.0–11.0)

0.008

0.176

  1. Data are presented as n (%) for dichotomic variables and median (IQR) for continuous variables. For the calculation of each percentage, the number of missing values was excluded from the denominator. The two groups were compared by non-parametric tests (chi-square test, Fisher exact test and Mann–Whitney U-test), as appropriate
  2. AID anti-inflammatory drug, CRP C-reactive protein, CT-scan, computed tomography scan, d days, GA general anesthesia, ICU Intensive care unit, IV intravenous, NSAID non-steroidal anti-inflammatory drug, WBC white blood cell
  3. aExcluding patients receiving both NSAIDs and CT