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Table 2 Clinical manifestationsfromcases of enterovirus71 infection in Korea between 2007 and 2012

From: Epidemiology and virologic investigation of human enterovirus 71 infection in the Republic of Korea from 2007 to 2012: a nationwide cross-sectional study

Clinical syndrome/Year 2007 2008 2009 2010 2011 2012 Total
n % n % n % N % N % n % n %
HFMD or herpangina 11 50.0 1 50.0 103 81.1 133 70.0 58 49.2 58 46.0 364 62.2
 Without complication 11 50.0 1 50.0 70 55.1 70 36.8 10 8.5 36 28.6 198 33.8
 With aseptic meningitis      33 26.0 63 33.2 42 35.6 18 14.3 156 26.7
 With encephalitis or ME          6 5.1 3 2.4 9 1.5
 With ADEM            1 0.8 1 0.2
Aseptic meningitis only 8 36.4    18 14.2 46 24.2 31 26.3 33 26.2 136 23.2
Encephalitis or ME only      2 1.6 6 3.2 7 5.9 4 3.2 19 3.2
Myocarditis          2 1.7    2 0.3
Sepsis      1 0.8 3 1.6 5 4.2 4 3.2 13 2.2
Othersa 3 13.6 1 50.0 3 2.4 2 1.1 15 12.7 27 21.4 51 8.7
Total 22 3.8 2 0.3 127 21.7 190 32.5 118 20.2 126 21.5 585 100.0
Death      2 1.6 2 1.1 1 0.8    5 0.9
  1. HFMD hand-foot-mouth disease, ADEM acute disseminated encephalomyelitis, ME meningoencephalitis
  2. aSymptoms such as fever, cold syndrome, abdominal pain, sore throat and manifestations of a suspected enterovirus infection