Safety and efficacy of liposomal amphotericin B for treatment of complicated visceral leishmaniasis in patients without HIV, North-West Ethiopia

Table 4 Comparison of changes from baseline to end of treatment laboratory and clinical characteristics between the treatment groups

Variables	Low dose liposomal amphotericin B (<24 mg/kg total dose) n = 86	High dose liposomal amphotericin B (24-35 mg/kg total dose) n = 61	P-value
	Median (and IQR)	Median (and IQR)
White blood cell (WBC) x 10³ cell/μl	1.65 (0.9 – 2.5)	1.7 (0.9 – 2.85)	0.7
Platelet x 10³ cell/μl	71.5 (37.8 – 142.5)	152 (92 – 238.5)	0.000
Spleen size in cm	4 (2 – 6.3)	4 (2 – 6.4)	0.7
Body temperature °C	2.3 (1.6 – 3.2)	2.2 (1.4 -3.2)	0.6

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