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Table 3 Laboratory variables at time of hospital admission: comparison between DENV co-infections and mono-infections

From: Impact of dengue virus (DENV) co-infection on clinical manifestations, disease severity and laboratory parameters

Characteristic

All patients

(n = 262) (%)

All mono-infections

(n = 222) (%)

All co-infectionsa

(n = 40) (%)

OR (95 % CI)

DENV-1 mono-infections

(n = 170) (%)

DENV-1 co-infectionsb

(n = 39) (%)

OR (95 % CI)

DENV-2 mono-infections

(n = 44) (%)

DENV-2 co-infectionsc

(n = 35) (%)

OR (95 % CI)

Leukopenia

175 (66.8)

149 (67.1)

26 (65)

0.91 (0.45-1.85)

121(71.2)

25 (64.1)

0.72 (0.35-1.51)

21 (47.7)

21 (60)

1.64 (0.67-4.04)

Platelet < 50,000/mm3

39 (14.9)

30 (13.5)

9 (22.5)

1.86 (0.81-4.29)

27(15.9)

9 (23.1)

1.59 (0.68-3.72)

1 (2.3)

7 (20)

10.75 (1.25-92.16)*

Raised haematocrit

142 (54.2)

117 (52.7)

25 (62.5)

1.50 (0.75-2.99)

88(51.8)

23 (59)

1.34 (0.66-2.71)

23 (52.3)

23 (65.7)

1.75 (0.7-4.37)

Raised uread

11 (4.6)

9 (4.5)

2 ( 5.4)

1.22( 0.25-5.88)

7(4.5)

2 (5.6)

1.25 (0.25-6.30)

2 (5.4)

2 (6.2)

1.17 (0.16-8.79)

Low sodium

9 (3.7)

7 (3.4)

2 (5.3)

1.58 (0.32-7.91)

6(3.8)

2 (5.4)

1.45 (0.28-7.48)

1 (2.5)

2 (6.1)

2.52 (0.22-29.05)

Low potassium

168 (68.9)

145 (70.4)

23 (60.5)

0.65 (0.32-1.32)

108(68.4)

22 (59.5)

0.68 (0.33-1.42)

31 (77.5)

21 (63.6)

0.51 (0.18-1.42)

Raised creatininee

32 (13.5)

22 (11.1)

10 (26.3)

2.87 (1.23-6.70)*

18(11.7)

10 (27)

2.80 (1.17-6.72)*

4 (10.8)

9 (27.3)

3.09 (0.85-11.24)

Raised bilirubin

12 (4.8)

10 (4.7)

2 (5.3)

1.12 (0.24-5.31)

9(5.6)

2 (5.4)

0.97 (0.2-4.67)

1 (2.4)

2 (6.1)

2.65 (0.23-30.51)

Low albumin

7 (2.8)

6 (2.8)

1 (2.6)

0.94 (0.11-8.01)

4(2.4)

1 (2.7)

1.11 (0.12-10.24)

2 (4.8)

1 (3)

0.63 (0.05-7.21)

Raised ASTf

133 (78.2)

114 (78.6)

19 (76)

0.86 (0.32-2.34)

90(81.1)

19 (79.2)

0.89 (0.30-2.65)

19 (65.5)

17 (77.3)

1.79 (0.51-6.29)

Raised ALT

153 (61)

133 (62.4)

20 (52.6)

0.67 (0.33-1.34)

108(65.9)

20 (54.1)

0.61 (0.30-1.26)

20 (47.6)

19 (57.6)

1.49 (0.60-3.74)

  1. Bold* type represents significance at p < 0.05
  2. aDENV-1/DENV-2 (n = 34), DENV-1/DENV-3 (n = 5), DENV-2/DENV-3 (n = 1); bDENV-1/DENV-2 (n = 34), DENV-1/DENV-3 (n = 5); cDENV-2/DENV-1 (n = 34), DENV-2/DENV-3 (n = 1)
  3. dData available for 238 cases, eData available for 237 cases, fData available for 170 cases