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Fig. 5 | BMC Infectious Diseases

Fig. 5

From: HIV-1 Tat protein vaccination in mice infected with Mycobacterium tuberculosis is safe, immunogenic and reduces bacterial lung pathology

Fig. 5

Tat vaccine administered to Mtb-infected mice is immunogenic. Serum samples of Mtb-infected (a) or Mtb-free (b) mice treated as shown in Fig. 1 were analyzed by ELISA for the presence of anti-Tat antibodies. Data are plotted as geometric mean ELISA titer ± SEM of 5 or 6 individual mice/group. The results shown are representative of two independent experiments. Statistical analysis was done by one-way ANOVA and Tukey’s multiple comparisons post-test *, P < 0.05, **, P < 0.01, ***, P < 0.001, differences respect to untreated Mtb-infected group (a) or to untreated Mtb-free group (b). In panel b, the difference between BCG-vaccinated and unvaccinated, Tat-treated groups is indicated

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