Variable | Total | Non-converters | Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|---|---|---|
N | n | % | Crude OR | 95 % CI | p-value | Adjusted OR | 95 % CI | p-value | |
Age, years | 10,506 | 1411 | |||||||
0–14 | 157 | 5 | 3.18 | Reference | |||||
15–30 | 4325 | 419 | 9.69 | 3.26 | 1.33–7.99 | 0.010 | 2.32 | 0.94–5.73 | 0.067 |
31–45 | 3801 | 596 | 15.68 | 5.65 | 2.31–13.8 | <0.000 | 3.77 | 1.53–9.31 | 0.004 |
46–60 | 1816 | 325 | 17.89 | 6.63 | 2.69–16.27 | <0.000 | 4.65 | 1.88–11.5 | 0.001 |
>60 | 407 | 66 | 16.22 | 5.88 | 2.32–14.89 | <0.000 | 4.56 | 1.79–11.6 | 0.001 |
Gender | 10,574 | 1411 | |||||||
Female | 4380 | 451 | 10.29 | Reference | Reference | ||||
Male | 6194 | 960 | 15.49 | 1.59 | 1.42–1.80 | <0.000 | 1.44 | 1.27–1.63 | <0.000 |
HIV | 10,574 | 1411 | |||||||
Negative | 7538 | 979 | 12.98 | Reference | Reference | ||||
Positive | 2192 | 341 | 15.56 | 1.23 | 1.08–1.41 | 0.002 | 1.41 | 1.22–1.62 | <0.000 |
Unknown | 844 | 91 | 10.78 | 0.81 | 0.64–1.02 | 0.069 | 0.74 | 0.58–0.94 | 0.013 |
Pretreatment smear grading | 10,574 | 1411 | |||||||
Scanty | 936 | 47 | 5.02 | Reference | Reference | ||||
AFB+ | 2271 | 173 | 7.76 | 1.56 | 1.12–2.17 | 0.009 | 1.64 | 1.17–2.28 | 0.004 |
AFB++ | 2227 | 240 | 10.78 | 2.28 | 1.65–3.15 | <0.000 | 2.42 | 1.75–3.35 | <0.000 |
AFB+++ | 4613 | 904 | 19.59 | 4.61 | 3.41–6.24 | <0.000 | 4.83 | 3.56–6.55 | <0.000 |
Not recorded | 527 | 47 | 8.92 | 1.85 | 1.22–2.82 | 0.004 | 1.86 | 1.22–2.84 | 0.004 |
Year | |||||||||
2007 | 1461 | 240 | 16.43 | Reference | Reference | ||||
2008 | 1670 | 249 | 14.91 | 0.89 | 0.73–1.08 | 0.244 | 0.81 | 0.66–0.99 | 0.044 |
2009 | 1764 | 247 | 14.00 | 0.83 | 0.68–1.00 | 0.056 | 0.75 | 0.62–0.92 | 0.006 |
2010 | 1560 | 151 | 9.68 | 0.54 | 0.44–0.67 | 0.000 | 0.52 | 0.41–0.64 | 0.000 |
2011 | 1382 | 177 | 12.61 | 0.75 | 0.61–0.92 | 0.007 | 0.71 | 0.57–0.88 | 0.002 |
2012 | 1460 | 185 | 12.67 | 0.74 | 0.60–0.91 | 0.004 | 0.68 | 0.55–084 | 0.000 |
2013 | 1277 | 162 | 12.69 | 0.74 | 0.59–0.92 | 0.006 | 0.75 | 0.60–0.94 | 0.012 |
Sub-district | 10,574 | 1411 | |||||||
Bitou | 913 | 103 | 11.28 | Reference | Reference | ||||
George | 3919 | 533 | 13.60 | 1.24 | 0.98–1.54 | 0.062 | 1.20 | 0.95–1.51 | 0.119 |
Hessequa | 6.83 | 93 | 13.62 | 1.24 | 0.92–1.67 | 0.160 | 1.28 | 0.94–1.74 | 0.117 |
Kannaland | 504 | 68 | 13.49 | 1.23 | 0.88–1.70 | 0.222 | 1.18 | 0.84–1.66 | 0.312 |
Knysna | 1131 | 143 | 12.64 | 1.14 | 0.87–1.49 | 0.347 | 1.13 | 0.85–1.48 | 0.398 |
Mossel Bay | 1699 | 241 | 14.18 | 1.29 | 1.01–1.66 | 0.037 | 1.28 | 1.00–1.66 | 0.050 |
Oudtshoorn | 1725 | 230 | 13.33 | 1.21 | 0.94–1.54 | 0.132 | 1.18 | 0.92–1.53 | 0.192 |