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Table 3 Logistic regression analyses to investigate sexual risk determinants associated with HSV-1 and HSV-2 seropositivitya

From: Herpes simplex virus type 1 and type 2 in the Netherlands: seroprevalence, risk factors and changes during a 12-year period

   HSV-1 HSV-2
N (%) OR [95 % CI]b aOR [95 % CI]c OR [95 % CI]b aOR [95 % CI]c
Number of recent partnersd
 0 partners 226 (6.28) Ref. Ref. Ref. Ref.
 1 partners 3031 (84.19) 1.39 [1.05-1.83] 1.12 [0.71-1.75] 1.28 [0.81-2.04] 0.52 [0.24-1.12]
 > = 2 partners 195 (5.42) 1.15 [0.75-1.74] 0.85 [0.50-1.46] 1.51 [0.82-2.78] 0.48 [0.21-1.12]
 Unknown 148 (4.11) 1.68 [1.10-2.59] 1.34 [0.84-2.13] 1.27 [0.65-2.48] 0.78 [0.37-1.64]
Sexual preference
 Heterosexual 3242 (90.06) Ref. Ref. Ref. Ref.
 Homo-/bisexual 47 (1.31) 1.10 [0.66-1.84] 1.23 [0.72-2.11] 2.31 [1.23-4.35] 1.94 [0.98-3.83]
 Unknown 311 (8.64) 0.78 [0.62-0.98] 0.87 [0.60-1.26] 0.58 [0.38-0.91] 0.35 [0.17-0.72]
Self-reported history of STI
 No 3326 (92.39) Ref. Ref. Ref. Ref.
 Yes, excluding genital herpes 123 (3.42) 1.18 [0.79-1.76] 1.18 [0.78-1.76] 1.75 [1.06-2.90] 1.66 [0.98-2.81]
 Yes, genital herpes 29 (0.81) 1.88 [0.78-4.50] 1.84 [0.75-4.53] 7.53 [3.20-17.69] 7.71 [3.19-18.60]
 Unknown 122 (3.39) 1.11 [0.73-1.68] 1.04 [0.69-1.58] 1.12 [0.60-2.09] 1.21 [0.66-2.22]
Age at sexual debut
 <=16 years 871 (24.19) Ref. Ref. Ref. Ref.
 17-20 years 1703 (47.31) 0.75 [0.63-0.89] 0.74 [0.62-0.88] 1.20 [0.88-1.63] 1.22 [0.88-1.69]
 > = 21 years 562 (15.61) 0.62 [0.51-0.76] 0.64 [0.52-0.78] 1.02 [0.74-1.41] 1.05 [0.74-1.49]
 Unknown 464 (12.89) 0.89 [0.72-1.09] 0.85 [0.70-1.04] 0.91 [0.61-1.38] 0.96 [0.63-1.46]
Condom use steady partnere
 Consistent 219 (13.13) Ref. - Ref. -
 Inconsistent 1068 (64.03) 0.96 [0.70-1.32] - 1.12 [0.65-1.92] -
 Unknown/no steady partner 381 (22.84) 0.91 [0.63-1.30] - 0.79 [0.43-1.45] -
Condom use casual partnere
 Consistent 80 (4.80) Ref. - Ref. -
 Inconsistent 68 (4.08) 1.25 [0.67-2.32] - 0.30 [0.07-1.25] -
 Unknown/no casual partner 1520 (91.13) 1.04 [0.66-1.63] - 0.62 [0.31-1.24] -
  1. Numbers and percentages were unweighted. Logistic regression analyses were unweighted, corrected for the complex survey design
  2. In bold: OR is statistically significant (p < 0.05)
  3. HSV herpes simplex virus; OR odds ratio; aOR adjusted odds ratio; CI confidence interval; Ref reference; STI sexually transmitted infection
  4. aOnly adults who ever had sexual intercourse were included. Adults were aged 17 to 44 years in Pienter-1 and 15 to 44 years in Pienter-2
  5. bOR adjusted for: gender, age, ethnicity and degree of urbanization
  6. cAdjusted for all variables including those presented in Table 2
  7. dNumber of partners in the past year for Pienter-1 and in the past 6 months for Pienter-2
  8. eCondom use in the past 6 months. Available for Pienter-2 only