Table 2 Bivariate analysis of prognostic factors of patients with bacteremia acquired in intensive care units
Variables | Median survival time (days) | 95 % CI | HR | 95 % CI | Death/total (%) | P |
|---|---|---|---|---|---|---|
Age > 60 years | ||||||
Yes | 5 | 0.00–10.82 | 1.67 | 1.08–2.58 | 37/53 (70) | 0.02 |
No | 20 | 11.07–28.93 | 1 | 47/88 (53) | ||
Sex | ||||||
Male | 9 | 4.32–13.69 | 1.49 | 0.95–2.35 | 56/87 (64) | 0.08 |
Female | 25 | 9.67–40.34 | 1 | 28/54 (52) | ||
APACHE II Score > 20 | ||||||
Yes | 10 | 3.48–16.52 | 1.11 | 0.72–1.70 | 39/60 (65) | 0.64 |
No | 15 | 5.10–24.9 | 1 | 45/81 (56) | ||
CHARLSON Score > 3 | ||||||
Yes | 15 | 1.78–28.22 | 1.18 | 0.76–1.84 | 31/48 (65) | 0.46 |
No | 11 | 5.32–16.68 | 1 | 53/93 (57) | ||
Co-morbid condition | ||||||
Diabetes mellitus | ||||||
Yes | 7 | a | 1.67 | 1.03–2.70 | 23/31 (74) | 0.03 |
No | 16 | 6.86–25.14 | 1 | 61/110 (55) | ||
Liver cirrhosis | ||||||
Yes | 5 | 0.01–9.99 | 1.58 | 0.96–2.59 | 21/28 (75) | 0.07 |
No | 16 | 4.30–27.70 | 1 | 63/113 (56) | ||
Cancer | ||||||
Yes | 18 | 0.00–39.72 | 0.87 | 0.52–1.46 | 18/33 (55) | 0.59 |
No | 10 | 5.01–14.99 | 1 | 66/108 (61) | ||
Solid organ transplant | ||||||
Yes | 5 | 0.98–9.02 | 1.31 | 0.80–2.15 | 21/30 (70) | 0.28 |
No | 16 | 7.22–24.78 | 1 | 63/111 (57) | ||
Hematopoietic stem cell transplant | ||||||
Yes | 7 | a | 0.87 | 0.12–6.26 | 1/2 (50) | 0.89 |
No | 11 | 4.21–17.79 | 1 | 83/139 (60) | ||
HIV infection | ||||||
Yes | a | a | 0.61 | 0.22–1.66 | 4/9 (44) | 0.33 |
No | 10 | 4.12–15.88 | 1 | 80/132 (61) | ||
Chronic renal disease | ||||||
Yes | 10 | 0.56–19.45 | 1.30 | 0.79–2.14 | 21/31 (68) | 0.29 |
No | 13 | 3.92–22.08 | 1 | 63/110 (57) | ||
Obstructive pulmonary disease | ||||||
Yes | 8 | 0.00–21.58 | 1.73 | 0.92–3.26 | 11/12 (92) | 0.09 |
No | 12 | 3.85–20.15 | 1 | 73/129 (57) | ||
Trauma | ||||||
Yes | a | a | 0.57 | 0.25–1.30 | 6/15 (40) | 0.18 |
No | 10 | 3.27–16.73 | 1 | 78/126 (62) | ||
Systemic arterial hypertension | ||||||
Yes | 8 | 2.39–13.61 | 1.16 | 0.75–1.80 | 33/56 (59) | 0.51 |
No | 15 | 6.39–23.61 | 1 | 51/85 (60) | ||
ICU length of stay previous to bacteremia > 8 days | ||||||
Yes | 20 | 8.90–31.10 | 0.78 | 0.51–1.21 | 37/65 (57) | 0.27 |
No | 9 | 5.20–12.80 | 1 | 47/76 (62) | ||
Initial site of infection | ||||||
Primary bloodstream | ||||||
Yes | 13 | 4.71–21.29 | 1.01 | 0.63–1.62 | 60/101 (59) | 0.97 |
No | 9 | 2.98–15.02 | 1 | 24/40 (60) | ||
Pneumonia | ||||||
Yes | 8 | 0.67–15.33 | 1.32 | 0.68–2.56 | 10/14 (71) | 0.41 |
No | 13 | 4.88–21.13 | 1 | 74/127 (58) | ||
Surgical site | ||||||
Yes | 13 | 4.22–21.78 | 1.22 | 0.58–2.52 | 76/130 (58) | 0.60 |
No | 9 | 3.53–14.47 | 1 | 8/11 (73) | ||
Urinary tract | ||||||
Yes | a | a | 0.05 | 0.00–10.63 | 0/3 (0) | 0.27 |
No | a | a | 1 | 84/138 (61) | ||
Skin and soft tissue | ||||||
Yes | 1 | a | 1.40 | 0.34–5.71 | 2/3 (67) | 0.64 |
No | 12 | 5.27–18.73 | 1 | 82/138 (59) | ||
Acinetobacter spp. | ||||||
Yes | 2 | 0.00–4,51 | 1.85 | 1.21–2.85 | 43/59 (73) | 0.005 |
No | 24 | 19.42–28,58 | 1 | 41/82 (50) | ||
IIAT | ||||||
Yes | 9 | 4.46–13.54 | 1.53 | 0.98–2.36 | 50/73 (68) | 0.057 |
No | 24 | 7.06–40.95 | 1 | 34/68 (50) | ||