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Table 1 Rates of hospitalisation, length of hospital stay, and rates of in-hospital death related to pneumonia in Scotland 5 years before introduction of PCV 7 and three years after introduction of PCV 13

From: Pneumonia hospitalisations in Scotland following the introduction of pneumococcal conjugate vaccination in young children

Age (years) <2 2–4 5–17 18–39 40–64 65–74 75–84 85+
Pneumonia Hospitalisation rate /100Ka (95 % CI)
 2000–2005 293 (280–306) 181 (173–190) 43 (41–45) 53 (51–54) 112 (110–114) 373 (365–380) 875 (861–889) 1909 (1872–1946)
 2010–2012 206 (191–221) 177 (166–188) 45 (42–48) 62 (59–64) 182 (179–186) 634 (621–647) 1426 (1402–1451) 2785 (2728–2842)
Lengths of hospital stay (days). Median (IQR)
 2000–2005 3 (1–5) 2 (1–4) 3 (1–5) 4 (2–6) 5 (3–10) 7 (4–14) 9 (4–19) 11 (5–25)
 2010–2012 2 (1–5) 2 (1–4) 2 (1–5) 3 (1–6) 5 (2–9) 6 (3–12) 7 (4–15) 9 (4–19)
Lengths of hospital stay (days) incl. readmissions within 14 days. Median, IQR
 2000–2005 3 (1–5) 2 (1–4) 3 (1–5) 4 (2–7) 5 (3–11) 7 (4–15) 9 (4–20) 12 (4–25)
 2010–2012 2 (1–5) 2 (1–4) 2 (1–5) 3 (1–7) 5 (2–9) 6 (3–12) 8 (4–16) 9 (4–19)
Reasons for admission coded as pneumococcal disease. %, 95 % CI
 2000–2005 9.3 (8.1–10.7) 3.3 (2.5–4.2) 4.1 (3.4–5.1) 6.8 (6.1–7.5) 6.1 (5.7–6.6) 3.8 (3.4–4.1) 2.3 (2.0–2.5) 1.1 (1.0–1.4)
 2010–2012 3.3 (2.3, 4.9) 1.1 (0.6–1.9) 2.5 (1.7–3.6) 3.5 (2.9–4.3) 2.9 (2.6–3.3) 1.7 (1.4–2.0) 1.0 (0.8–1.2) 0.7 (0.5–0.9)
Deaths from pneumonia (primary cause, all patients)b %, 95 % CI
 2000–2005 0 0.06 (0.008, 0.4) 0.2 (0.1, 0.6) 0.7 (0.5, 1.0) 3.5 (3.2, 3.8) 6.9 (6.5, 7.4) 13.1 (12.5, 13.6) 25.8 (24.9, 26.6)
 2010–2012 0 0 0.3 (0.1, 0.9) 0.3 (0.1, 0.6) 1.4 (1.2, 1.7) 3.4 (3.0, 3.7) 6.2 (5.8, 6.6) 15.7 (15.0, 16.5)
Deaths from pneumonia as proportion of all deaths (primary cause)c %, 95 % CI
 2000–2005 0 2.4 (0.3, 15.1) 3.1 (1.3, 7.4) 5.2 (3.7, 7.2) 7.4 (6.7, 8.2) 8.7 (8.1, 9.3) 14.1 (13.5, 14.7) 26.3 (25.4, 27.2)
 2010–2012 0 0 11.1 (3.6, 29.3) 4.3 (2.2, 8.4) 6.0 (5.1, 7.1) 8.2 (7.4, 9.2) 12.0 (11.2, 12.8) 24.0 (22.9, 25.1)
Deaths from pneumonia (any cause, all patients)d %, 95 % CI
 2000–2005 0.8 (0.5, 1.3) 0.6 (0.3, 1.0) 2.3 (1.8, 3.0) 3.7 (3.2, 4.3) 18.8 (18.1, 19.5) 36.9 (35.9, 37.8) 52.8 (52.0, 53.6) 66.1 (56.1, 67.0)
 2010–2012 0.7 (0.3, 1.6) 0.2 (0.05, 0.8) 2.1 (1.4, 3.2) 2.4 (1.9, 3.1) 8.5 (8.0, 9.1) 14.9 (14.2, 15.6) 21.6 (20.9, 22.3) 36.1 (35.1, 37.1)
  1. aThe hospitalisation rates have been calculated after excluding data where patient’s health board was coded as “other”
  2. bDeaths with pneumonia as a primary cause as a proportion of the whole population
  3. cDeaths with pneumonia as a primary cause as a proportion of the deaths reported in this population
  4. dDeaths with pneumonia as any cause as a proportion of the whole population
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BMC Infectious Diseases

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