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Table 2 Antimicrobial (beta lactam) susceptibility of the breakthrough viridans group streptococcal strains

From: Breakthrough viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients receiving levofloxacin prophylaxis in a Japanese hospital

         No. of isolates at each MIC, mg/L
Antimicrobial agent No. of isolates tested Susceptible range mg/L No. of the susceptible strains Resistant range mg/L No. of the resistant strains MIC50, mg/L MIC90, mg/L ≤0.03 0.06 ≤0.06; CFPM 0.12 0.25 ≤0.25; CAZ 0.5 1 2 4 8 16
Penicillin 28 ≤0.12 22 (79 %) >4 0 0.06 0.25 8 9 5 3 2 0 1 0 0 0
Ceftazidime 22 NA NA NA NA 0.5 2     5 7 7 1 0 2 0
Cefepime 22 ≤1 21 (95 %) >4 0 0.12 0.25   9 7 4 0 1 1 0 0 0
Meropenem 22 ≤0.5 22 (100 %) >1 0 ≤0.03 0.12 17 2 2 1 0 0     
            ≤0.25/4 0.5/4 1/4 2/4 4/4 8/4 >16/4
Piperacillin/tazobactam 22 ≤8/4 22 (100 %) >16/4 0 ≤0.25/4 ≤0.25/4     21 1 0 0 0 0 0
  1. MIC minimum inhibitory concentration, CFPM cefepime, CAZ ceftazidim, NA not available