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Table 4 Multivariable multinomial logistic regression models for factors associated with seroconversion and prevalent HCV infection in BC-HTC, Canada 1990-2012a, b

From: Twin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort

Variables

Seroconverters

Prevalent HCV

 

ORs (95 % CI)

ORs (95 % CI)

Sex

  

 Female

1.00

1.00

 Male

1.25 (1.19-1.31)

2.06 (2.02-2.10)

Birth year

  

  < 1945

1.00

1.00

 1945-1954

3.38 (2.78-4.11)

3.79 (3.67-3.92)

 1955-1964

6.22 (5.19-7.44)

3.23 (3.13-3.34)

 1965-1974

9.86 (8.26-11.78)

1.64 (1.58-1.70)

 1975-1984

11.76 (9.83-14.07)

0.70 (0.67-0.73)

  ≥ 1985

6.53 (5.34-7.99)

0.48 (0.44-0.51)

HIV infection at baselinec

  

 No/Unknown

1.00

1.00

 Yes

7.92 (7.05-8.89)

4.80 (4.47-5.15)

HBV at baselinec

  

 No/Unknown

1.00

1.00

 Yes

2.33 (2.00-2.71)

0.69 (0.63-0.75)

Active TB at baselinec

  

 No/Unknown

1.00

1.00

 Yes

1.00 (0.62-1.62)

1.01 (0.81-1.25)

Material deprivation quintile at baselinec

  

 Unknown

3.51 (2.96-4.17)

5.38 (5.07-5.70)

 Q1 (most privileged)

1.00

1.00

 Q2

1.20 (1.06-1.31)

1.22 (1.18-1.27)

 Q3

1.24 (1.13-1.36)

1.36 (1.32-1.41)

 Q4

1.62 (1.48-1.76)

1.60 (1.55-1.65)

 Q5 (most deprived)

1.99 (1.83-2.15)

1.98 (1.92-2.04)

Mental illness at baselinec

  

 No/Unknown

1.00

1.00

 Yes

1.18 (1.12-1.25)

0.69 (0.67-0.72)

Illicit drugs use at baseline

  

 No/Unknown

1.00

1.00

 Yes

21.00 (19.80-22.38)

5.03 (4.91-5.16)

Problematic alcohol use at baseline

  

 No/Unknown

1.00

1.00

 Yes

2.11 (2.00-2.23)

1.67 (1.63-1.72)

  1. aAdjusted for health authority and year of diagnosis; bExcluding unknown gender and health authority. cBaseline is defined as time of diagnosis for HCV positive, and date of last negative for HCV negative