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Table 2 Characteristics of HCV positive and negative individuals, BC-HTC, Canada, 1990-2013

From: Twin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort

  HCV + ve group HCV -ve group
  M24 Seroa >M24 Serob Prevalent HCV All Positives All Negatives
  N = 3628 N = 3436 N = 48717 N = 55781 N = 988381
  N (%) N (%) N (%) N (%) N (%)
Age at baselinec      
  < 15 17 (0.5) 1 (0.0) 420 (0.9) 438 (0.8) 20289 (2.1)
 15-24 962 (26.5) 410 (11.9) 2410 (5.0) 3782 (6.8) 145326 (14.7)
 25-34 1477 (40.7) 1234 (35.9) 9907 (20.3) 12618 (22.6) 259347 (26.2)
 35-44 827 (22.8) 1106 (32.2) 16534 (33.9) 18467 (33.1) 220626 (22.3)
 45-54 275 (7.6) 522 (15.2) 13068 (26.8) 13865 (24.9) 163134 (16.5)
  ≥ 55 70 (1.9) 163 (4.7) 6378 (13.1) 6611 (11.9) 179659 (18.2)
Median [IQR] 30 [24-37] 35 [28-43] 42 [34-49] 41 [33-48] 37 [28-50]
Age at 1st test      
  < 15 100 (2.8) 84 (2.4) 421 (0.9) 605 (1.1) 25860 (2.6)
 15-24 1485 (40.9) 1128 (32.8) 2422 (5.0) 5035 (9.0) 189747 (19.2)
 25-34 1225 (33.8) 1278 (37.2) 9927 (20.4) 12430 (22.3) 261056 (26.4)
 35-44 605 (16.7) 712 (20.7) 16590 (34.1) 17907 (32.1) 208398 (21.1)
 45-54 169 (4.7) 195 (5.7) 13063 (26.8) 13427 (24.1) 147688 (14.9)
  ≥ 55 44 (1.2) 39 (1.1) 6294 (12.9) 6377 (11.4) 155632 (15.8)
Median [IQR] 26 [20-34] 28 [22-35] 42 [34-49] 40 [32-48] 35 [26-48]
Birth year      
  < 1945 31 (0.9) 35 (1.0) 3102 (6.4) 3168 (5.7) 95848 (9.7)
 1945-1964 776 (21.4) 1037 (30.2) 32133 (66.0) 33946 (60.9) 310845 (31.5)
 1965-1974 1176 (32.4) 1214 (35.3) 9493 (19.5) 11883 (21.3) 209956 (21.2)
  ≥ 1975 1645 (45.3) 1150 (33.5) 3989 (8.2) 6784 (12.2) 371732 (37.6)
Sex      
 Female 1728 (47.6) 1380 (40.2) 16741 (34.4) 19849 (35.6) 551952 (55.8)
 Male 1900 (52.4) 2056 (59.8) 31970 (65.6) 35926 (64.4) 436287 (44.1)
 Unknown 0 (0.0) 0 (0.0) 6 (0.0) 6 (0.0) 142 (0.0)
Year of diagnosis      
 1990-1994 85 (2.3) 4 (0.1) 3978 (8.2) 4067 (7.3) 3913 (0.4)
 1995-1999 726 (20.0) 353 (10.3) 17936 (36.8) 19015 (34.1) 104863 (10.6)
 2000-2004 1177 (32.4) 939 (27.3) 11733 (24.1) 13849 (24.8) 172888 (17.5)
 2005-2009 994 (27.4) 1280 (37.3) 9130 (18.7) 11404 (20.4) 272886 (27.6)
 2010-2013 646 (17.8) 860 (25.0) 5940 (12.2) 7446 (13.4) 433831 (43.9)
HIV/AIDS at baseline      
 Unknown 3450 (95.1) 3207 (93.3) 47568 (97.6) 54225 (97.2) 984182 (99.6)
 Yes 178 (4.9) 229 (6.7) 1149 (2.4) 1556 (2.8) 4199 (0.4)
HIV/AIDS (ever)      
 Unknown 3264 (90.0) 3104 (90.3) 46257 (95.0) 52625 (94.3) 983694 (99.5)
 Yes 364 (10.0) 332 (9.7) 2460 (5.0) 3156 (5.7) 4687 (0.5)
HBV at baseline      
 No/Unknown 3528 (97.2) 3349 (97.5) 48197 (98.9) 55074 (98.7) 974223 (98.6)
 Yes 100 (2.8) 87 (2.5) 520 (1.1) 707 (1.3) 14158 (1.4)
HBV (ever)      
 No/Unknown 3453 (95.2) 3326 (96.8) 46927 (96.3) 53706 (96.3) 968459 (98.0)
 Yes 175 (4.8) 110 (3.2) 1790 (3.7) 2075 (3.7) 19922 (2.0)
Active TB at baseline      
 No/Unknown 3621 (99.8) 3428 (99.8) 48634 (99.8) 55683 (99.8) 986909 (99.9)
 Yes 7 (0.2) 8 (0.2) 83 (0.2) 98 (0.2) 1472 (0.1)
Active TB (ever)      
 No/Unknown 3611 (99.5) 3415 (99.4) 48466 (99.5) 55492 (99.5) 986473 (99.8)
 Yes 17 (0.5) 21 (0.6) 251 (0.5) 289 (0.5) 1908 (0.2)
Material deprivation quintile at baseline      
 Unknown 96 (2.7) 79 (2.3) 2316 (4.8) 2491 (4.5) 14773 (1.5)
 Q1 (most privileged) 452 (12.5) 444 (12.9) 6247 (12.8) 7143 (12.8) 214007 (21.7)
 Q2 526 (14.5) 463 (13.5) 7500 (15.4) 8489 (15.2) 187587 (19)
 Q3 531 (14.6) 585 (17.0) 8522 (17.5) 9638 (17.3) 192265 (19.5)
 Q4 876 (24.2) 774 (22.5) 10580 (21.7) 12230 (21.9) 197116 (19.9)
 Q5 (most deprived) 1147 (31.6) 1091 (31.8) 13552 (27.8) 15790 (28.3) 182633 (18.5)
Social deprivation quintile at baseline      
 Unknown 96 (2.7) 79 (2.3) 2316 (4.8) 2491 (4.5) 14773 (1.5)
 Q1 (most privileged) 271 (7.5) 283 (8.2) 5302 (10.9) 5856 (10.5) 180214 (18.2)
 Q2 349 (9.6) 337 (9.8) 6194 (12.7) 6880 (12.3) 175098 (17.7)
 Q3 540 (14.9) 463 (13.5) 8094 (16.6) 9097 (16.3) 175715 (17.8)
 Q4 703 (19.4) 720 (21.0) 9972 (20.5) 11395 (20.4) 201551 (20.4)
 Q5 (most deprived) 1669 (46.0) 1554 (45.2) 16839 (34.6) 20062 (36) 241030 (24.4)
Mental health at baselined      
 No/Unknown 2199 (64.5) 2096 (65.0) 40934 (86.7) 45229 (84.0) 729398 (88.0)
 Yes 1209 (35.5) 1130 (35.0) 6297 (13.3) 8636 (16.0) 99054 (12.0)
Mental health 3yrs pre-baselined      
 No/Unknown 2590 (76.0) 2653 (82.2) 43518 (92.1) 48761 (90.5) 781042 (94.3)
 Yes 818 (24.0) 573 (17.8) 3713 (7.9) 5104 (9.5) 47410 (5.7)
Illicit drug use at baselined      
 No/Unknown 910 (26.7) 942 (29.2) 33036 (69.9) 34888 (64.8) 770499 (93.0)
 Yes 2498 (73.3) 2284 (70.8) 14195 (30.1) 18977 (35.2) 57953 (7.0)
Illicit drug use 3yrs pre-baselined      
 No/Unknown 1084 (31.8) 1433 (44.4) 36193 (76.6) 38710 (71.9) 795325 (96.0)
 Yes 2324 (68.2) 1793 (55.6) 11038 (23.4) 15155 (28.1) 33127 (4.0)
Problematic alcohol use at baselined      
 No/Unknown 2083 (61.1) 1896 (58.8) 38178 (80.8) 42157 (78.3) 777271 (93.8)
 Yes 1325 (38.9) 1330 (41.2) 9053 (19.2) 11708 (21.7) 51181 (6.2)
Problematic alcohol use 3yrs pre-baselined      
 No/Unknown 2521 (74.0) 2555 (79.2) 41709 (88.3) 46785 (86.9) 802492 (96.9)
 Yes 887 (26.0) 671 (20.8) 5522 (11.7) 7080 (13.1) 25960 (3.1)
  1. a24-month Sero: Individuals who seroconverted within 24 months of the last negative test
  2. bIndividuals who seroconverted after 24 months of the last negative test
  3. cBaseline is defined as date of diagnosis (i.e. first HCV positive test or case report) for HCV positive individuals, and date of last negative test result for HCV negative individuals
  4. dMental health, drug misuse, alcohol misuse data was available up to 2012