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Table 2 Factors potentially associated with HCV treatment initiation over time

From: Hepatitis C treatment initiation in HIV-HCV coinfected patients

  P-value of the between groups effect P-value of the time effect*
First treatment vs retreatment <0.001 <0.001
Age (≤ vs > 40 years) 0.001 0.210
Gender <0.001 0.522
HIV risk factors (homosexual vs other) <0.001 0.519
HCV duration (< vs ≥ 1 year <0.001 <0.001
HCV genotype (1 vs non-1) 0.190 <0.001
Liver fibrosis (F0-F2 vs F3-F4) <0.001 <0.001
CDC stage (A-B vs C) <0.001 <0.001
CD4 cell count (< vs ≥ 350) <0.001 0.318
HIV RNA (≤ vs >200 copies/mL) <0.001 0.758
  1. *The p-value associated with the group effect indicated whether the probability of HCV treatment initiation differed between different groups. The p-value associated with the interaction effect indicated whether different evolution of HCV treatment initiation existed according to the groups. For example, the probability of HCV treatment initiation is significantly higher among patients with liver fibrosis F3-F4 (p < 0.001) and evolution over time differed between those F0-F2 and F3-F4 (p < 0.001)