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Table 3 Unadjusted associations between individual characteristics [n (%)] of children 6 months to <5 years (n = 263) or 5 to <18 years (n = 120), hospitalized with community-acquired pneumonia and length of stay (LOS) or intensive care unit (ICU) admission

From: Association of sputum microbiota profiles with severity of community-acquired pneumonia in children

   LOS ICU admission
<4 days ≥ 4 days   No Yes  
Characteristic N (%) (%) (%) P value (%) (%) P value
Age 6 months to <5 years
Demographic
  Race/Ethnicity     0.35    0.64
  White 28 (10.6) 10.6 10.9   10.1 15.4  
  Black 210 (79.8) 81.4 75.0   80.6 73.1  
  Other 25 (9.5) 8.0 14.1   9.3 11.5  
 Gender     0.87    0.67
  Female 121 (46.0) 45.7 46.9   45.6 50.0  
  Male 124 (54.0) 54.3 53.1   54.4 50.0  
Fall/winter season 157 (59.7) 59.3 60.9 0.82 60.7 50.0 0.29
 Environmental tobacco smoke exposure 27 (10.4) 11.8 6.3 0.21 9.9 15.4 0.32
 Medical History
  Asthma/reactive airway disease 126 (47.9) 44.7 57.8 0.07 46.8 57.7 0.29
  Chronic conditions other than asthma 63 (24.0) 22.1 29.7 0.22 23.6 26.9 0.71
  Prior antibiotics 59 (22.4) 22.6 21.9 0.90 22.4 23.1 0.93
  Pneumococcal vaccinea 256 (98.5) 98.5 98.4 0.97 98.7 96.0 0.29
 Respiratory virus positive
  RSV 110 (41.8) 42.7 39.1 0.61 43.9 23.1 0.04
  Rhinovirus 89 (33.8) 36.2 26.6 0.16 35.4 19.2 0.10
Age 5 to <18 years
Demographic
  Race/Ethnicity     0.81    0.73
  White 19 (15.8) 16.5 14.6   16.7 12.5  
  Black 93 (77.5) 76.0 80.5   76.0 83.3  
  Other 8 (6.7) 7.6 4.9   7.3 4.2  
 Gender     0.05    0.16
  Female 50 (41.7) 35.4 53.7   38.5 54.2  
  Male 70 (58.3) 64.6 46.3   61.5 45.8  
 Fall/winter season 68 (56.7) 58.2 53.7   57.3 54.2 0.78
 Environmental tobacco smoke exposure 17 (14.2) 15.2 12.2 0.66 14.6 12.5 1.00
Medical History
  Asthma/reactive airway disease 77 (64.2) 73.4 46.3 0.003 64.6 62.5 0.85
  Chronic conditions other than asthma 29 (24.2) 19.0 34.2 0.07 20.8 37.5 0.09
  Prior antibiotics 23 (19.2) 16.5 24.4 0.30 19.8 16.7 0.73
  Pneumococcal vaccineb 91 (76.5) 83.5 62.5 0.01 80.2 60.9 0.05
Respiratory virus positive
  RSV 13 (10.8) 12.7 7.3 0.37 9.4 16.7 0.30
  Rhinovirus 59 (49.2) 55.7 36.6 0.05 46.9 58.3 0.32
  1. aReceipt of at least one or more doses prior to enrollment, missing data for 3 subjects. Bold indicates a significant P value of <0.05
  2. bReceipt of at least one or more doses prior to enrollment, missing data for 1 subject