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Table 3 Clinical manifestations of severe dengue according to serotype

From: Serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in Vitória, Brazil

Clinical manifestation

DENV-1

DENV-2

DENV-4

All three serotypes

 

n/N

P-value

n/N

P-value

n/N

P-value

n/N

Any neurological disorders (%)

1/17 (5.9)

1.00b

1/10 (10.0)

0.53b

0/5 (0)

1.00b

2/32 (6.3)

Any cardiac disorders (%)

1/17 (5.9)

1.00b

0/10 (0)

1.00b

0/5 (0)

1.00b

1/32 (3.1)

Any signs of plasma leakage (%)

6/14 (42.9)

0.90a

3/7 (42.9)

1.00b

2/4 (50.0)

1.00b

11/25 (44.0)

 Hemoconcentration (%)

2/14 (14.3)

0.35b

3/7 (42.9)

0.30b

1/4 (25.0)

1.00b

6/25 (24.0)

 Cavity effusion (%)

1/14 (7.1)

1.00b

0/7 (0)

1.00b

1/4 (25.0)

0.30b

2/25 (8.0)

 Hypoproteinemia (%)

3/14 (21.4)

0.23b

0/7 (0)

0.53b

0/4 (0)

1.00b

3/25 (12.0)

Any sign of hemorrhage (%)

12/16 (75.0)

0.69b

6/8 (75.0)

1.00b

2/5 (40.0)

0.29b

20/29 (69.0)

 Positive tourniquet test (%)

8/11 (72.7)

0.60b

3/4 (75.0)

1.00b

0/2 (0)

0.11b

11/17 (64.7)

 Hematuria (%)

1/11 (9.1)

1.00b

0/4 (0)

1.00b

1/2 (50.0)

0.23b

2/17 (11.8)

 Petechiae (%)

3/11 (27.3)

0.63b

3/5 (60.0)

0.27b

0/2 (0)

0.53b

6/18 (33.3)

 Menorrhagia (%)

0/11 (0)

0.39b

1/5 (20.0)

0.28b

0/2 (0)

1.00b

1/18 (5.6)

 Gingival bleeding (%)

2/12 (16.7)

1.00b

1/4 (25.0)

1.00b

0/2 (0)

1.00b

3/18 (16.7)

 Epistaxis (%)

1/11 (9.1)

0.52b

1/4 (25.0)

1.00b

1/2 (50.0)

0.33b

3/17 (17.6)

  1. aPearson chi-square test; bFisher’s exact chi-square test