Table 2 Comparison of Clostridium difficile infected patients’ presentations between those who were treated with adjunctive intracolonic vancomycin and those who received therapy without intracolonic vancomycin

Total Number

26 (20.5 %)

101 (79.5 %)

 Severe Disease

7 (26.9 %)

12 (11.9 %)

0.11

 Moderate Disease

19 (73.1 %)

89 (88.1 %)

0.70

Age (years + SD)

67 ± 8

70 ± 13

0.31

Male Sex

25 (96.2 %)

82 (81.2 %)

0.07

Average Severity Score Index for Total Group

5.69 ± 1.4

5.02 ± 1.0

0.03

 Severe Disease

7.58 ± 0.98

7.08 ± 0.29

0.24

 Moderate Disease

5.00 + 0.75

4.74 + 0.75

0.17

Past Medical History

 Recent surgery within last 6 weeks

9 (34.6 %)

25 (24.7 %)

0.31

 History of CDI within the past 12 months

7 (26.9 %)

11 (10.9 %)

0.06

Comorbidities

 Diabetes mellitus

13 (50.0 %)

34 (33.7 %)

0.12

 Coronary artery disease

9 (34.7 %)

26 (25.7 %)

0.37

 Congestive heart failure

7 (15.4 %)

18 (17.8 %)

0.30

 COPD

9 (34.6 %)

25 (24.8 %)

0.31

 Malignancy

8 (20.7 %)

30 (29.7 %)

0.92

 Cirrhosis

1 (3.8 %)

5 (5.0 %)

1.00

Admission Medications

 Proton pump inhibitors

13 (68.4 %)

62 (57.4 %)

0.45

 Aspirin

8 (42.1 %)

36 (34.0 %)

0.46

 H2 blockers

4 (21.1 %)

35 (32.4 %)

0.42

 Corticosteroids

3 (15.8 %)

33 (30.1 %)

0.27

Laboratory Values within the first 72 h of the diagnosis of CDI

 WBC (cells/mm³)

27.2 ± 14.9

24.1 ± 16.9

0.36

 Hgb (g/L)

10.1 + 1.9

10.0 ± 3.1

0.84

 Albumin (g/dL)

1.7 ± 0.5

1.8 ± 0.5

0.55

 BUN (mg/dL)

46.4 ± 28.2

42.3 ± 33.0

0.51

 Creatinine (mg/dL)

2.2 ± 1.8

2.2 ± 1.8

0.97

Prior antibiotics within 8 weeks of diagnosis of CDI

24 (92.3 %)

94 (93.1 %)

0.76