TY - JOUR AU - Wang, Caixia AU - Jing, Haiyan AU - Sha, Dan AU - Wang, Weibo AU - Chen, Jianpeng AU - Cui, Yangang AU - Han, Junqing PY - 2016 DA - 2016/06/14 TI - HBV-associated intrahepatic cholangiocarcinoma with high serum alpha-fetoprotein: a case report with review of literature JO - BMC Infectious Diseases SP - 295 VL - 16 IS - 1 AB - Intrahepatic cholangiocarcinoma (ICC) is a rare malignant tumor. The etiology of ICC remains poorly understood. Recently, hepatitis B virus (HBV) infection has been implicated as a potential risk factor for ICC, particularly in HBV-endemic areas. Elevation of serum alpha-fetoprotein (AFP) is seen in approximately 20 % of ICC patients. However, serum AFP levels higher than 10,000 ng/mL have only been reported in a few ICC patients. We report an unusual case of HBV-associated ICC occurring in a male with a markedly elevated serum AFP. SN - 1471-2334 UR - https://doi.org/10.1186/s12879-016-1643-7 DO - 10.1186/s12879-016-1643-7 ID - Wang2016 ER -