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Table 6 Incidence and clearance of oral HPV infections

From: The incidence, clearance and persistence of non-cervical human papillomavirus infections: a systematic review of the literature

Author (ref) Population, age (years) Incidence (95 % CI) Clearance
   Unit Any HPV HR 16 18 Infection type Unit of clearance Any HPV HR 16 18
Males             
Edelstein [45] Male students, median 20 % at 1y 12.3 % (NTS, first)
(7.0–21.3)
- 0.8
(0.1–5.7)
2.7
(0.7–10.2)
- - - - - -
Kero [48] Male partners of pregnant women, 19–46 per 100py - - 6.0
(2.9–9.2)
1.2
(0.2–3.4)
- - - - - -
Kero [30]a Male partners of pregnant women, 20–52 % at 7 years 14.3 % (NTS)
(4.8–30.3)
- - - Prevalent % at 7 years 100 % (TS)
(64.4–100)
- - -
Kero [46]a Male partners of pregnant women, 20–52 % at 7 years 69.2 % (TS)
(59.5–77.2)
- - - Prevalent per 100py 3.8 (TS)
(1.6–6.1)
- 4.9
(2.3–7.4)
1.4
(0–2.7)
Rintala [50] Male partners of pregnant women, 20–52 % at 24 m - ~10 % (NTS, first) - - Prevalent % at 24 m - ~5 % (NTS) - -
Videla [23] HIV + ve MSM, 20- > 69
HIV + ve MSW, 20- > 69
per 100py 6.1 (NTS, first)
(4.2–8.4)
5.7
(3.0–9.7)
- - - Prevalent per 100py 19.3 (NTS)
(12.8–27.7)
15.8
(7.6–29.0)
- -  
Darwich [47] HIV + ve MSM, 20- > 69
HIV + ve MSW, 20- > 69
per 100py - - 1.0
(0.4–2.0)
2.6
(1.1–5.4)
0.2
(0–1.0)
0.7
(0.1–2.4)
Prevalent % at 24 m 48.3 % (TS)
(35.2–61.6)
34 %
(17.9–54.3)
- 22.7 per 100py
(11.3–40.6)
9.1 per 100py
(1.8–26.5)
Kreimer [44] HIV-ve men, 18–70 per 100py 6.7 (NTS, first)
(5.5–8.0)
3.0
(2.2–3.8)
1.0
(0.6–1.6)
0.0
(0–0.4)
- - - - - -
Women             
Pickard [49] Female students, 18–30 per 100py 6.8 (TS)
(3.7–9.8)
- - - Prevalent % at 3 m 60.6 (TS)
(42.1–77.1)
76.9
(46.2–95.0)-
100
(15.8–100)-
-
D’Souza [15] HIV-ve women
HIV + ve women
per 100py 20.4 (TS)
(8.4–44.4)
39.6
(25.2–57.6)
- - - Prevalent % at 6 m 20.0 (NTS)
(0.5–71.6)
40.0
(22.7–59.4)
- - -
Kero [30] Pregnant women, 19–46 % at 7 years 14.3 % (NTS)
(5.4–28.5)
- - - Prevalent % at 7 years 100 % (TS)
(29.2–100)
- - -
Rintala [50] Pregnant women, 19–46 % at 24 m - ~10 % (NTS, first) - - Prevalent % at 24 m - 0 % (NTS) - -
Men and women            
Kurose [52] Male/female volunteers, 3–85 - - - - - Prevalent % at 30 m 50.0 (TS)
(6.8–93.2)
- 100 (1 sample only) -
  1. Abbreviations: MSM men who have sex with men, MSW men who have sex with women, py person-years, y years, m months, TS type-specific incidence defined as at least one positive test for any HPV type or HR-HPV type not detected at baseline, NTS non-type-specific incidence defined as at least one positive test for any HPV type or HR-HPV type among those negative for any HPV DNA or any HR-HPV DNA at baseline
  2. aStudy [30] considered a subset of men (46/131) included in [46]. Study [30] reported HPV status at baseline and at 7 years, whereas study [46] considered HPV status at baseline and all subsequent follow-up visits (i.e., 2 m, 6 m, 24 m, 36 m, and 7y)