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Table 6 Incidence and clearance of oral HPV infections

From: The incidence, clearance and persistence of non-cervical human papillomavirus infections: a systematic review of the literature

Author (ref)

Population, age (years)

Incidence (95 % CI)

Clearance

  

Unit

Any HPV

HR

16

18

Infection type

Unit of clearance

Any HPV

HR

16

18

Males

            

Edelstein [45]

Male students, median 20

% at 1y

12.3 % (NTS, first)

(7.0–21.3)

-

0.8

(0.1–5.7)

2.7

(0.7–10.2)

-

-

-

-

-

-

Kero [48]

Male partners of pregnant women, 19–46

per 100py

-

-

6.0

(2.9–9.2)

1.2

(0.2–3.4)

-

-

-

-

-

-

Kero [30]a

Male partners of pregnant women, 20–52

% at 7 years

14.3 % (NTS)

(4.8–30.3)

-

-

-

Prevalent

% at 7 years

100 % (TS)

(64.4–100)

-

-

-

Kero [46]a

Male partners of pregnant women, 20–52

% at 7 years

69.2 % (TS)

(59.5–77.2)

-

-

-

Prevalent

per 100py

3.8 (TS)

(1.6–6.1)

-

4.9

(2.3–7.4)

1.4

(0–2.7)

Rintala [50]

Male partners of pregnant women, 20–52

% at 24 m

-

~10 % (NTS, first)

-

-

Prevalent

% at 24 m

-

~5 % (NTS)

-

-

Videla [23]

HIV + ve MSM, 20- > 69

HIV + ve MSW, 20- > 69

per 100py

6.1 (NTS, first)

(4.2–8.4)

5.7

(3.0–9.7)

-

-

-

Prevalent

per 100py

19.3 (NTS)

(12.8–27.7)

15.8

(7.6–29.0)

-

-

 

Darwich [47]

HIV + ve MSM, 20- > 69

HIV + ve MSW, 20- > 69

per 100py

-

-

1.0

(0.4–2.0)

2.6

(1.1–5.4)

0.2

(0–1.0)

0.7

(0.1–2.4)

Prevalent

% at 24 m

48.3 % (TS)

(35.2–61.6)

34 %

(17.9–54.3)

-

22.7 per 100py

(11.3–40.6)

9.1 per 100py

(1.8–26.5)

Kreimer [44]

HIV-ve men, 18–70

per 100py

6.7 (NTS, first)

(5.5–8.0)

3.0

(2.2–3.8)

1.0

(0.6–1.6)

0.0

(0–0.4)

-

-

-

-

-

-

Women

            

Pickard [49]

Female students, 18–30

per 100py

6.8 (TS)

(3.7–9.8)

-

-

-

Prevalent

% at 3 m

60.6 (TS)

(42.1–77.1)

76.9

(46.2–95.0)-

100

(15.8–100)-

-

D’Souza [15]

HIV-ve women

HIV + ve women

per 100py

20.4 (TS)

(8.4–44.4)

39.6

(25.2–57.6)

-

-

-

Prevalent

% at 6 m

20.0 (NTS)

(0.5–71.6)

40.0

(22.7–59.4)

-

-

-

Kero [30]

Pregnant women, 19–46

% at 7 years

14.3 % (NTS)

(5.4–28.5)

-

-

-

Prevalent

% at 7 years

100 % (TS)

(29.2–100)

-

-

-

Rintala [50]

Pregnant women, 19–46

% at 24 m

-

~10 % (NTS, first)

-

-

Prevalent

% at 24 m

-

0 % (NTS)

-

-

Men and women

           

Kurose [52]

Male/female volunteers, 3–85

-

-

-

-

-

Prevalent

% at 30 m

50.0 (TS)

(6.8–93.2)

-

100 (1 sample only)

-

  1. Abbreviations: MSM men who have sex with men, MSW men who have sex with women, py person-years, y years, m months, TS type-specific incidence defined as at least one positive test for any HPV type or HR-HPV type not detected at baseline, NTS non-type-specific incidence defined as at least one positive test for any HPV type or HR-HPV type among those negative for any HPV DNA or any HR-HPV DNA at baseline
  2. aStudy [30] considered a subset of men (46/131) included in [46]. Study [30] reported HPV status at baseline and at 7 years, whereas study [46] considered HPV status at baseline and all subsequent follow-up visits (i.e., 2 m, 6 m, 24 m, 36 m, and 7y)