Clinical feature | Diarrhoea-associated HUS (N = 38) | Non-diarrhea-associated HUS (N = 9) |
---|---|---|
Time first symptom to admittance (median, days) | 6 (4–9) | 5 (2–10) |
Age at admittance (median, months/years)a | 31 (range; 5 months–15 years)a | 18 (range; 7 months–6 years)a |
Duration of initial hospitalization (median, days) | 15 (11–24) | 16 (8–42) |
Duration of total time hospitalizedb (median, days) | 18 (12–24) | 16 (8–53) |
Prodromal diarrhea (n, %) | 37 (97 %) | 2 (22 %) |
Prodromal bloody diarrhea (n, %) | 27 (71 %) | 2 (22 %) |
Hypertension at admittance (n, %) | 4 (24 %) (N = 17) | 2 (33 %) (N = 6) |
Hypertension registered during admittance (n, %) | 30 (83 %) (N = 36) | 8 (100 %) (N = 8) |
Oligoanuria (n, %) | 29 (76 %) | 5 (56 %) |
Death acute phase (n, %) | 2 (5 %) | 0 (0 %) |
Non-renal complications | ||
Neurological complications (n, %) | 9 (24 %) | 2 (22 %) |
Cardiac complications (n, %) | 2 (5 %) | 0 (0 %) |
Respiratory complications (n, %) | 10 (26 %) | 2 (22 %) |
Gastrointestinal complications (n, %) | 5 (13 %) | 1 (11 %) |
Sepsis (n, %) | 11 (29 %) | 3 (33 %) |
Renal outcome | ||
Proteinuria at first follow-up (n, %) | 16 (50 %) (N = 32) | 7 (78 %) |
Proteinuria ≥ 1 year after initial admission (n, %) | 8 (38 %) (N = 21) | 4 (57 %) (N = 7) |
Hypertension at first follow-up (n, %) | 10 (31 %) (N = 32) | 5 (56 %) |
Hypertension ≥ 1 year after initial admission (n, %) | 5 (26 %) (N = 19) | 4 (80 %) (N = 5) |
Chronic kidney disease (n, %) | 2 (5 %) | 1 (11 %) |
End-stage renal disease (ESRD) | 1 (3 %) | 0 (0 %) |