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Table 3 Distribution of HLA DRB1*-DQB1* haplotypes in patients with localised cutaneous leishmaniasis and population controls

From: Association of HLA class I and II genes with cutaneous leishmaniasis: a case control study from Sri Lanka and a systematic review

 

Haplotype frequencya (N)

   

Haplotype

Patients

Controls

P

Pc b

OR (95 % CI)

DRB1*04 DQB1*02

0.0000 (0)

0.0185 (5)

0.03

0.09

NA

DRB1*07 DQB1*02

0.0000 (0)

0.0185 (5)

0.03

0.09

NA

DRB1*15 DQB1*02

0.0000 (0)

0.0148 (3)

0.12

0.18

NA

DRB1*15 DQB1*03

0.0255 (6)

0.0277 (8)

0.56

0.56

0.73 (0.25–2.1)

DRB1*15 DQB1*05

0.0328 (8)

0.0501 (14)

0.18

0.22

0.55 (0.23–1.3)

DRB1*15 DQB1*06

0.0584 (16)

0.1519 (41)

0.00

0.00

0.3 (0.2–.0.6)

  1. N indicates the number of patients or controls with the given haplotype
  2. aOnly the haplotypes present at a minimum of 0.01 % in the patients or controls are listed
  3. b Pc, corrected P values for the number of alleles tested, calculated using the False Discovery Rate method