| Allele frequency |  |  |  | |
---|---|---|---|---|---|
Allele | Patients | Controls | P value* | Pc ** | OR (95Â % CI) |
HLA-A a | 2n = 18 | 2n = 62 |  |  |  |
  A a 02 | 0.4444 | 0.2581 | 0.13 | 0.29 | 2.3 (0.77–6.84) |
  A a 03 | 0.1667 | 0.0807 | 0.28 | 0.43 | 2.3 (0.49–10.64) |
  A a 11 | 0.0556 | 0.0161 | 0.39 | 0.44 | 3.6 (0.21–60.41) |
  A a 23 | 0.0556 | 0.0161 | 0.39 | 0.39 | 3.6 (0.21–60.41) |
  A a 24 | 0.1111 | 0.0484 | 0.33 | 0.43 | 2.46 (0.38–15.99) |
  A a 29 | 0.0000 | 0.1774 | 0.06 | 0.28 | NAa |
  A a 31 | 0.0556 | 0.1774 | 0.2 | 0.36 | 0.3 (0.03–2.27) |
  A a 33 | 0.1111 | 0.0161 | 0.09 | 0.27 | 7.6 (0.65–89.5) |
  A a 68 | 0.0000 | 0.2097 | 0.03 | 0.31 | NAa |
HLA-B | 2n = 60 | 2n = 62 |  |  |  |
  B a 07 | 0.25 | 0.4839 | 0.007 | 0.13 | 0.36 (0.17–0.77) |
  B a 08 | 0.0333 | 0.0161 | 0.62 | 0.73 | 2.1 (0.19–23.83) |
  B a 14 | 0.0167 | 0.0000 | 0.49 | 0.85 | NA |
  B a 15 | 0.0833 | 0.0484 | 0.44 | 0.83 | 1.8 (0.41–7.84) |
  B a 25 | 0.0167 | 0.0000 | 0.49 | 0.78 | NA |
  B a 27 | 0.0333 | 0.0323 | 0.97 | 1.02 | 1.03 (0.14–7.6) |
  B a 35 | 0.1167 | 0.0645 | 0.32 | 0.67 | 1.92 (0.53–6.92) |
  B a 37 | 0.0167 | 0.0000 | 0.49 | 0.72 | NA |
  B a 38 | 0.0167 | 0.0645 | 0.18 | 1.16 | 0.25 (0.03–2.26) |
  B a 39 | 0.0333 | 0.0000 | 0.24 | 1.14 | NA |
  B a 40 | 0.1167 | 0.0968 | 0.72 | 0.81 | 1.23 (0.39–3.91) |
  B a 42 | 0.0000 | 0.0484 | 0.24 | 0.81 | NA |
  B a 44 | 0.1 | 0.0323 | 0.16 | 1.52 | 3.33 (0.64–17.22) |
  B a 51 | 0.0333 | 0.0807 | 0.26 | 0.62 | 0.39 (0.07–2.11) |
  B a 52 | 0.0333 | 0.0000 | 0.24 | 0.91 | NA |
  B a 53 | 0.0167 | 0.0000 | 0.49 | 0.67 | NA |
  B a 55 | 0.0167 | 0.0000 | 0.49 | 0.62 | NA |
  B a 57 | 0.0333 | 0.0000 | 0.24 | 0.76 | NA |
  B a 58 | 0.0333 | 0.0323 | 1.0 | 1.0 | 1.03 (0.14–7.59) |
HLA-DRB1 | 2n = 34 | 2n = 88 |  |  |  |
  DRB1 a 03 | 0.0000 | 0.0114 | 1.0 | 1.17 | NA |
  DRB1 a 04 | 0.0000 | 0.1023 | 0.06 | 0.21 | NA |
  DRB1 a 07 | 0.0000 | 0.0682 | 0.18 | 0.43 | NA |
  DRB1 a 09 | 0.0000 | 0.0227 | 1.0 | 1.75 | NA |
  DRB1 a 14 | 0.0000 | 0.0227 | 1.0 | 1.4 | NA |
  DRB1 a 15 | 1.0000 | 0.7614 | 0.002 | 0.01 | NA |
  DRB1 a 16 | 0.0000 | 0.0114 | 1.0 | 1.0 | NA |
HLA-DQB1 | 2n = 358 | 2n = 346 |  |  |  |
 DQB1a02 | 0.1229 | 0.159 | 0.11 | 0.28 | 0.71 (0.46–1.08) |
 DQB1a03 | 0.2458 | 0.2139 | 0.2 | 0.34 | 1.25 (0.88–1.78) |
 DQB1a04 | 0.0000 | 0.0116 | 0.06 | 0.29 | NA |
 DQB1a05 | 0.3045 | 0.3035 | 0.89 | 0.89 | 0.98 (0.71–1.35) |
 DQB1a06 | 0.3268 | 0.3121 | 0.62 | 0.78 | 1.08 (0.79–1.49) |