Table 3 Predictors of paradoxical reaction on univariate analysis

Age in years Mean ± SD

27.295 ± 10.958

30.866 ± 13.446

0.125

−1.004

8.145

Duration of illness (days) Mean ± SD

42.932± 21.583

52.495± 27.538

0.028

0.276

18.850

Gender (female)

26 (59.1 %)

39 (40.2 %)

0.037

2.148

1.04

4.436

HIV positive

11(25 %)

2(2.1 %)

<0.001

15.833

3.334

75.184

Fever

43(97.7 %)

95(97.9 %)

0.936

0.905

0.080

10.255

Headache

39(88.6 %)

92(94.8 %)

0.183

0.424

0.116

1.548

Seizure

12(27.3 %)

36(37.1 %)

0.253

0.635

0.291

1.387

Altered Sensorium

15(34.1 %)

29(29.9 %)

0.618

1.213

0.567

2.593

Decreased vision

10(22.7 %)

25(25.8 %)

0.698

0.847

0.366

1.960

Hemiparesis

7(15.9 %)

16(16.5 %)

0.930

0.958

0.363

2.526

Paraparesis

2(4.5 %)

10(10.3 %)

0.341

0.414

0.087

1.976

Meningeal signs

41(93.2 %)

84(86.6 %)

0.253

2.115

0.571

7.837

Lymphadenopathy

10(22.7 %)

3(3.1 %)

0.001

9.216

2.393

35.496

Diplopia

17(38.6 %)

42(43.3 %)

0.603

0.825

0.398

1.707

Cranial Nerve involvement

27(61.4 %)

53(54.6 %)

0.455

1.319

0.638

2.727

Papilloedema

13(29.5 %)

42(43.3 %)

0.121

0.549

0.256

1.177

Hydrocephalus

13(29.5 %)

40(41.2 %)

0.184

0.598

0.279

1.282

Basal Exudates

9(20.5 %)

29(29.9 %)

0.242

0.603

0.257

1.413

Tuberculoma

15(34.1 %)

36(37.1 %)

0.729

0.876

0.415

1.850

Infarct

7(15.9 %)

18(18.6 %)

0.703

0.830

0.319

2.161

Optochiasmatic Arachnoiditis

7(15.9 %)

14(14.4 %)

0.820

1.122

0.418

3.008

Spinal cord

2(4.5 %)

10(10.3 %)

0.256

0.414

0.087

1.976

CRP

19(43.2 %)

38(39.2 %)

0.653

1.180

0.573

2.430

Stage 3 TBM

15(34.1 %)

29(29.9 %)

0.618

1.213

0.567

2.593

Baseline BI (<12)

34(77.3 %)

59(60.8 %)

0.056

2.190

0.970

4.944

Definite TBM

20(45.5 %)

34(35.1 %)

0.312

1.544

.748

3.189

Good outcome (BI>12)

32(72.7 %)

59(64.8 %)

0.171

0.582

0.267

1.268

ESR mm in 1 h Mean ± SD

27.818 ± 4.876

27.093 ± 7.593

0.497

−3.194

1.743

CSF Cells/μL Mean ± SD

200.864 ± 121.261

184.505 ± 208.810

0.630

83.265

56.548

CSF protein (mg/dl) Mean ± SD

188.5382 ± 115.145

283.2649 ± 542.511

0.254

−68.924

258.377

CSF sugar (mg/dl) Mean ± SD

33.620 ± 18.231

36.086 ± 18.617

0.465

4.193

9.125