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Table 3 Nested case control analysis of persistent versus cleared bacteremia: clinical syndrome and clinical parameters at the time of repeat blood culture collection

From: Sending repeat cultures: is there a role in the management of bacteremic episodes? (SCRIBE study)

 

Cleared bacteremia (n = 118)

Persistent bacteremia (n = 118)

P

Clinical Syndrome n(%)

   

 Endovascular

28 (23.7)

52 (44.1)

<0.001

  Endocarditis

9 (7.6)

18 (15.3)

0.066

  Central line/device/graft

19 (16.1)

34 (28.8)

0.019

 Extravascular

68 (57.6)

54 (45.8)

0.068

  Abdominal

19 (16.1)

10 (8.5)

0.074

  Cardio-respiratory

18 (15.3)

11 (9.3)

0.17

  Genito-urinary

20 (16.9)

7 (5.9)

0.008

  SSTI

9 (7.6)

15 (12.7)

0.20

  Epidural abscess/discitis

1 (0.9)

7 (5.9)

0.036

  Septic arthritis

1 (0.9)

5 (4.2)

0.121

 Unknown

22 (18.6)

12 (10.2)

0.064

Clinical parameters at time of repeat culture [present/total (%)]

   

 SIRS

51/105 (48.6)

40/98 (40.8)

0.27

 Leukocytosis

50/118 (42.4)

48/114 (42.1)

0.97

 Fever

34/106 (32.1)

25/99 (25.3)

0.28

 Physician concern of instability

36/105 (34.3)

25/96 (26.0)

0.20

  1. NOTE: P values were calculated using the Chi square or Fisher’s exact test. P value threshold for significance was <0.05 (statistically significant values are bolded). SSTI, skin and soft tissue infection (including cellulitis, necrotizing soft tissue infection, cutaneous and muscular hematomas, ulcers, osteomyelitis and surgical site infections); SIRS systemic inflammatory response syndrome