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Table 4 Incident tuberculosis among household contacts in 1178 households in function of the index case and household characteristics

From: A prospective longitudinal study of tuberculosis among household contacts of smear-positive tuberculosis cases in Lima, Peru

 

Incident TB in the household

Crude odds ratio (95%CI)

 

Yes

No

Index case characteristics

   

 Sex

   

  Female

86 (12.3 %)

611 (87.7 %)

0.7 (0.5–1.0)

  Male

77 (16.0 %)

404 (84.0 %)

1

 Age

   

  18–27

96 (14.4 %)

571 (85.6 %)

1.0 (0.6–1.5)

  28–37

34 (14.2 %)

206 (85.8 %)

0.7 (0.4–1.4)

  38–47

11 (11.0 %)

89 (89.0 %)

0.9 (0.5–1.4)

  >48

22 (13.8 %)

149 (87.1 %)

1

 Cough

   

  Yes

160 (14.1 %)

975 (85.9 %)

1

  No

3 (7.0 %)

40 (93.0 %)

0.5 (0.1–1.5)

 Time from symptoms to treatmenta

   

  0–30 days

50 (10.0 %)

448 (90.0 %)

1

  >30 days

113 (16.6 %)

567 (83.4 %)

1.8 (1.3–2.5)

 Smear positivity at diagnosisb

   

  Scanty

1 (2.5 %)

39 (97.5 %)

0.2 (0.0–1.3)

  +/++

110 (12.7 %)

755 (87.3 %)

1

  +++

52 (19.1 %)

221 (80.9 %)

1.6 (1.1–2.3)

 Treatment type

   

  Drug sensitive

159 (13.7 %)

1003 (86.3 %)

0.5 (0.2–1.5)

  Multidrug resistant

4 (25.0 %)

12 (75.0 %)

1

Household characteristics

   

 Past TB episodesc in the household

   

  Yes

41 (19.0 %)

175 (81.0 %)

1.6 (1.1–2.4)

  No

122 (12.7 %)

840 (87.3 %)

1

 Recent TB episodesd in the household

   

  Yes

23 (20.4 %)

90 (79.7 %)

1.7 (1.0–2.8)

  No

140 (13.2 %)

925 (86.9 %)

1

 Persons per room (median, IQR)

2.5 (1.8–3.8)

2 (1.5–3)

1.1 (1.0–1.2)

  1. a = time from symptoms was calculated from the date the participant reported to start coughing until the date of treatment registered, bscanty = 1–9 acid fast bacilli (AFB) in 100 fields, +/++ = from 10 AFB in 100 fields to 10 AFB per field in at least 50 fields, +++ = more than 10 acid fast bacilli in at least 20 fields,smear positivity was classified following standard national TB program guidelines13, c = a TB episode in a HHC more than two years before the diagnosis of the index case, d = a TB episode within two years before the index case diagnosis