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Table 6 Risk factors for nosocomial RSV infection

From: Clinical characterisation and phylogeny of respiratory syncytial virus infection in hospitalised children at Red Cross War Memorial Children’s Hospital, Cape Town

Risk factor Nosocomial N = 22 n/n(%) Crude OR (95 % CI) p value Adjusted b OR (95 % CI) p value
Age      
  < 6 months 9/160(5.6) 1   1  
  ≥ 6 months 13/66(19.7) 4.11 (1.66–10.18) 0.002 3.35 (1.20–9.36) 0.02
Gender      
 Male 9/117(7.7) 1   1  
 Female 13/109(11.9) 1.63 (0.67–3.97) 0.29 1.90 (0.69–5.24) 0.22
Weight-for-age z score      
 Appropriate 10/134(7.5) 1   1  
 Underweight 12/92(13) 1.86 (0.78–4.51) 0.17 1.55 (0.56–4.3) 0.40
Pre-existing conditions other than HIV infection      
 Yes 17/113(15) 1   1  
 No 5/113(4.4) 0.23 (0.09–0.74) 0.01 0.40 (0.13–1.27) 0.12
HIV status a      
 Unexposed uninfected 15/164(9.2) 1   1  
 Exposed uninfected 4/47(8.5) 0.93 (0.29–2.93) 0.89 1.26 (0.36–4.40) 0.72
 Exposed infected 1/4(25.0) 3.31 (0.32–33.84) 0.31 4.31 (0.34–55.44) 0.26
RSV genotype      
 N A1 14/127(11.0) 1   1  
 NA2 0/9(0) NA   NA  
 ON1 5/45(11.1) 1.01 (0.34–2.98) 0.34 0.84 (0.26–2.73) 0.77
 BA4 3/45(6.7) 0.58 (0.16–2.11) 0.16 0.70 (0.18–2.81) 0.62
  1. OR (95 % CI) Odds ratio (95 % confidence interval)
  2. a HIV status not known in 11; n/n = stratum specific prevalence. NA = Not applicable
  3. b Model adjusted for nutritional status, HIV status, age, sex, genotype and pre-existing conditions