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Table 2 Ninety-day mortality in incident Staphylococcus aureus bacteremia patients with versus without chronic heart failure (CHF)

From: Chronic heart failure and mortality in patients with community-acquired Staphylococcus aureus bacteremia: a population-based cohort study

  Number Mortality % (95 % CI) Crude MRR (95 % CI) Adjusteda MRR (95 % CI)
CHF     
 Absent 2248 30.4 (28.6–32.4) 1.00 (ref.) 1.00 (ref.)
 Present 390 44.6 (39.8–49.7) 1.60 (1.36–1.89) 1.24 (1.04–1.48)
CHF-related conditions     
 CHF absent 2248 30.4 (28.6–32.4) 1.0 (ref.) 1.0 (ref.)
 Cardiomyopathy 52 30.8 (20.1–45.2) 0.99 (0.60–1.62) 1.04 (0.63–1.72)
 Valvular heart disease 70 60.0 (48.8–71.4) 2.44 (1.79–3.34) 1.73 (1.26–2.38)
 Myocardial infarction 85 41.2 (31.6–52.4) 1.45 (1.04–2.05) 1.17 (0.83–1.65)
 Atrial fibrillation 66 50.0 (38.7–62.5) 1.81 (1.27–2.57) 1.21 (0.85–1.73)
 None of the above 117 41.0 (32.7–50.5) 1.46 (1.09–1.95) 1.12 (0.83–1.50)
CHF severityb     
 CHF absent 2248 30.4 (28.6–32.4) 1.00 (ref.) 1.00 (ref.)
 Non-users 99 32.2 (24.1–42.5) 1.08 (0.76–1.54) 0.99 (0.69–1.42)
 Low dose (≤40 mg/day) 39 38.5 (25.3–55.5) 1.30 (0.78–2.16) 0.83 (0.50–1.40)
 Medium dose (41–80 mg/day) 82 42.7 (32.8–54.1) 1.52 (1.08–2.14) 1.13 (0.80–1.59)
 High dose (81–159 mg/day) 75 53.3 (42.6–64.9) 2.05 (1.49–2.83) 1.55 (1.11–2.14)
 Very high dose (≥160 mg/day) 95 54.7 (45.1–64.9) 2.10 (1.59–2.79) 1.62 (1.21–2.18)
Duration of CHF     
 CHF absent 2248 30.4 (28.6–32.4) 1.00 (ref.) 1.00 (ref.)
  < 3 years 188 50.0 (43.1–57.3) 1.83 (1.48–2.27) 1.43 (1.14–1.78)
  ≥ 3- < 6 years 81 39.5 (29.8–51.0) 1.39 (0.98–1.99) 1.01 (0.71–1.46)
  ≥ 6- < 10 years 69 42.0 (31.4–54.5) 1.52 (1.05–2.21) 1.22 (0.84–1.78)
  ≥ 10 years 52 36.5 (25.1–51.1) 1.25 (0.79–1.97) 0.97 (0.61–1.54)
  1. CI confidence interval, MRR mortality rate ratio
  2. aAdjusted for age, sex, conditions included in the modified Charlson Comorbidity Index (excluding the condition in question), hypertension, alcohol related conditions, marital status, and antibiotic treatment within 30 days of admission
  3. bDefined by daily loop-diuretic dosage