Total (n = 117) | No HIV co-infection (n = 73) | HIV co-infection (n = 44) | P | |
---|---|---|---|---|
n (%) a | n (%) a | n (%) a | ||
Sex | <0.001 | |||
Male | 88 (75) | 44 (60) | 44 (100) | |
Female | 29 (25) | 29 (40) | 0 (0) | |
Mean age, year (SD) | 34 (10) | 31 (9) | 41 (8) | <0.001 |
Symptomatic acute HCV | 0.825 | |||
No | 68 (58) | 43 (59) | 25 (57) | |
Yes | 49 (42) | 30 (41) | 19 (43) | |
ALT level at acute HCV detection, log10 IU/L | 2.2 (0.5) | 2.1 (0.5) | 2.4 (0.5) | 0.006 |
Estimated duration of infection at acute HCV detection | 0.236 | |||
<26 weeks | 69 (59) | 40 (55) | 29 (66) | |
≥26 weeks | 48 (41) | 33 (45) | 15 (34) | |
Interferon lambda 4 genotype (rs12979860) | 0.185 | |||
TT/CT | 56 (48) | 37 (51) | 19 (43) | |
CC | 59 (50) | 37 (49) | 23 (53) | |
Unknown | 2 (2) | 0 (0) | 2 (4) | |
HCV RNA level at acute HCV detection | 0.031 | |||
<400,000 IU/mL | 78 (67) | 54 (74) | 24 (55) | |
≥400,000 IU/mL | 39 (33) | 19 (26) | 20 (45) | |
HCV genotype | 0.682 | |||
Genotype 1 | 67 (57) | 41 (56) | 26 (59) | |
Genotype 3 | 40 (34) | 27 (37) | 13 (29) | |
Other genotypesb | 8 (7) | 4 (5) | 4 (9) | |
Unknown genotype | 2 (2) | 1 (1) | 1 (2) |