Variable | Normal | CIN1 | CIN2 | CIN3 | SCC | P-Value |
---|---|---|---|---|---|---|
(n = 16968) | (n = 458) | (n = 247) | (n = 181) | (n = 44) | ||
overalla | 10.0 (9.5–10.4) | 81.2 (77.6–84.8) | 86.2 (81.9–90.5) | 94.5 (91.2–97.8) | 95.4 | 0.001 |
High riska | 9.1 (8.7–9.5) | 64.0 (59.6–68.4) | 65.2 (59.3–71.1) | 80.1 (74.3–85.9) | 88.6 (79.2–98.0) | 0.001 |
Othersa | 166 (1.0) | 17.2 (13.8–20.6) | 21.0 (15.9–26.1) | 14.4 (9.3–19.5) | 6.8 | 0.17 |
Singlea infectiona | 8.3 (7.9–8.7) | 56.8 (51.9–60.9) | 55.5 (49.3–61.7) | 72.4 (65.9–78.9) | 77.3 (64.9–89.7) | 0.001 |
Multiple infectiona | 1.8 (1.6–2.0) | 24.4 (20.5–28.3) | 30.8 (25.1–36.5) | 22.1 (16.1–28.1) | 18.2 (6.8–29.6) | 0.5 |
Unidentifieda | 0.7 | 7.0 (4.7–9.3) | 8.1 (4.7–11.5) | 6.6 (3.0–10.2) | 9.1 (0.6–17.6) |  |
HR-HPV | Â | Â | Â | Â | Â | Â |
 HPV-16a | 2.2 (1.9–2.4) | 21.0 (17.3–24.7) | 16.2 (11.6–20.8) | 33.1 (26.3–39.9) | 45.4 (30.7–60.1) | 0.001 |
 HPV-52a | 2.3 (2.1–2.5) | 20.1 (16.4–23.8) | 19.4 (14.5–24.3) | 11.0 (6.5–15.5) | 15.9 (5.1–26.7) | 0.025 |
 HPV-58a | 1.4 | 13.1 (10.0–16.2) | 14.6 (10.2–20.0) | 19.9 (14.1–25.7) | 18.2 (6.8–29.6) | 0.04 |
 HPV-18a | 0.6 | 5.2 (3.2–7.2) | 1.6 (0.03–3.2) | 17.7 (12.1–23.3) | 18.2 (6.8–29.6) | 0.001 |
 HPV-51 | 92 (0.5) | 16 (3.5) | 12 (4.8) | - | - |  |
 HPV-68 | 84 (0.5) | 23 (5.0) | 8 (3.2) | 7 (3.9) | - |  |
 HPV-33 | 80 (0.5) | 20 (4.4) | 20 (8.1) | 4 (2.2) | - |  |
 HPV-39 | 76 (0.4) | 28 (6.1) | 8 (3.2) | 4 (2.2) | - |  |
 HPV-31 | 48 (0.3) | 6 (1.3) | 4 (1.6) | 5 (2.8) | - |  |
 HPV-56 | 40 (0.2) | 8 (1.7) | 8 (3.2) | 4 (2.2) | - |  |
 HPV-59 | 40 (0.2) | 8 (1.7) | - | 4 (2.2) | 4 (9.1) |  |
 HPV-45 | 4 (0.02) | 6 (1.3) | - | 2 (1.1) | - |  |
 HPV-35 | 9 (0.05) | 3 (0.6) | - | - | - |  |
PHR-HPV | Â | Â | Â | Â | Â | Â |
 HPV-53 | 128 (0.7) | 28 (6.1) | 20 (8.1) | - | - |  |
 HPV-81 | 52 (0.3) | 24 (5.2) | 19 (7.7) | 12 (6.6) | - |  |
 HPV-66 | 44 (0.2) | 8 (1.7) | 8 (3.2) | 4 (2.2) | 3 (6.8) |  |
Others | Â | Â | Â | Â | Â | Â |
 HPV-61 | 24 (0.1) | - | 3 (1.2) | - | - |  |
 HPV-11 | 24 (0.1) | - | 4 (1.6) | 4 (2.2) | - |  |
 HPV-6 | 12 (0.07) | - | - | 4 (2.2) | - |  |
 HPV-43 | 8 (0.05) | 4 (0.9) | - | 3 (1.6) | - |  |
 HPV-44 | 8 (0.05) | 4 (0.9) | - | - | - |  |
 HPV-42 | 4 (0.02) | 2 (0.4) | - | 3 (1.6) | - |  |
 HPV-55 | 4 (0.02) | 3 (0.6) | - | - | - |  |
 HPV-40 | 4 (0.02) | - | - | - | - |  |
 HPV-67 | 1 (0.005) | - | - | - | - |  |
 HPV-69 | 1 (0.005) | - | - | - | - |  |
 HPV-70 | 2 (0.01) | - | - | - | - |  |
 HPV-71 | 3 (0.01) | - | - | - | - |  |
 HPV-82 | 6 (0.03) | - | - | - | - |  |
 HPV-83 | 2 (0.01) | - | - | - | - |  |