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Table 3 30 day all-cause mortality in relation to disease acquisition, severity, focus and time period

From: Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993–2011: an observational study

Characteristic No. of deaths within 30 days 30-day mortality within category (%) Age-, sex- and comorbidity-adjusteda
Odds ratio 95 % CI p Mortality risk (%) 95 % CI
Place of acquisition
 Community acquired 34 10.6 1 Reference   10.9 7.6–14.3
 Health-care associated 12 17.0 1.58 0.65–3.20 0.35 14.7 6.9–22.4
 Hospital acquired 5 27.8 3.13 0.92–10.43 0.07 25.2 6.7–43.9
Severity
 Sepsis without organ failure 14 5.2 1 Reference   5.4 2.7–8.02
 Severe sepsis 23 21.0 5.19 2.44–11.10 <0.001 20.2 13.5–27.4
 Septic shock 14 37.8 13.58 5.32–34.60 <0.001 35.0 21.6–49.0
 p for trend      <0.001   
Pitt bacteremia score
 0 12 9.5   Reference   9.4 4.5–14.3
 1 7 5.4 0.47 0.17–1.28 0.14 4.9 1.4–8.3
 2 8 11.1 1.45 0.53–3.94 0.47 12.7 4.9–20.5
 ≥3 24 28.2 5.10 2.12–11.65 <0.001 29.8 20.7–39.0
 p for trend      <0.001   
Time period
 1993–2002 17 12.7 1 Reference   13.5 7.9–19.2
 2003–2011 34 12.1 0.77 0.43–1.61 0.59 11.8 8.2–15.3
Time to antibioticsb
 <6 hours 33 14.1 1 Reference   11.9 8.5–15.3
 >6 hours 18 11.5 1.17 0.58–2.34 0.65 13.2 8.1–18.4
  1. aAdjusted for Charlson Comorbidity Index: 0, 1–2 and ≥3 bAlso adjusted for severity