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Table 5 Sensitivity of the different tools for IgG, IgM and IgA detection

From: Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

  Plasma Saliva Urine
IPC ELISA IPC ELISA RDT IPC ELISA RDT
IgG Primary 16.1 % (13/81) 13.2 % (19/144) 8.3 % (12/144) 5.6 % (8/143) 1.4 % (2/143)
  Secondary 72.9 % (124/170) 68 % (208/306) 48 % (147/306) 56.8 % (171/301) 39.2 % (118/301)
  p-value a <0.001 <0.001 <0.001 <0.001 <0.001
IgM Primary 31.2 % (24/77) 33.3 % (48/144) 11.1 % (16/144) 0 % (0/143) 0 % (0/143)
  Secondary 37.1 % (62/167) 34 % (104/306) 7.5 % (23/306) 0 % (0/301) 0 % (0/301)
  p-value a 0.365 0.891 0.206 1 1
IgA Primary 12.7 % (10/79) 2.9 % (4/140) 2.1 % (3/140) 4.2 % (6/143) 4.2 % (6/143)
  Secondary 53.2 % (91/171) 30.5 % (92/302) 6.6 % (20/302) 38.5 % (116/301) 14.3 % (43/301)
  p-value a <0.001 <0.001 0.049 <0.001 0.002
  1. The sensitivity of the different tools for IgG, IgM and IgA detection in plasma, urine and saliva is presented according to the patients’ immune status
  2. a Comparison of sensitivity between primary and secondary infection