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Table 5 Sensitivity of the different tools for IgG, IgM and IgA detection

From: Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

 

Plasma

Saliva

Urine

IPC ELISA

IPC ELISA

RDT

IPC ELISA

RDT

IgG

Primary

16.1 % (13/81)

13.2 % (19/144)

8.3 % (12/144)

5.6 % (8/143)

1.4 % (2/143)

 

Secondary

72.9 % (124/170)

68 % (208/306)

48 % (147/306)

56.8 % (171/301)

39.2 % (118/301)

 

p-value a

<0.001

<0.001

<0.001

<0.001

<0.001

IgM

Primary

31.2 % (24/77)

33.3 % (48/144)

11.1 % (16/144)

0 % (0/143)

0 % (0/143)

 

Secondary

37.1 % (62/167)

34 % (104/306)

7.5 % (23/306)

0 % (0/301)

0 % (0/301)

 

p-value a

0.365

0.891

0.206

1

1

IgA

Primary

12.7 % (10/79)

2.9 % (4/140)

2.1 % (3/140)

4.2 % (6/143)

4.2 % (6/143)

 

Secondary

53.2 % (91/171)

30.5 % (92/302)

6.6 % (20/302)

38.5 % (116/301)

14.3 % (43/301)

 

p-value a

<0.001

<0.001

0.049

<0.001

0.002

  1. The sensitivity of the different tools for IgG, IgM and IgA detection in plasma, urine and saliva is presented according to the patients’ immune status
  2. a Comparison of sensitivity between primary and secondary infection