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Table 1 Number of included studies and ranges of initiation and completion rates per study population

From: Initiation and completion rates for latent tuberculosis infection treatment: a systematic review

Study population Short treatment regimens Long treatment regimens Short/long treatment regimens combined  
  n Range rates (%) n Range rates (%) n Range rates (%) N
Initiation rates
 Prospective studies (n = 20 unique articles; some present data for more than one population and more than one treatment regimen)
 General 1 [23] 86 2 [18, 24] 44–99 1 [25] 26 4
 Case contacts 0 3 [2628] 40–85 1 [25] 53 4
 Healthcare workers 1 [19] 98 0 0 1
 Homeless 0 2 [29, 30] 76–90 1 [25] 34 3
 PWID 0 3 [3133] 52–91 0 3
 HIV infected 0 2 [34, 35] 90–92 1 [36] 91 3
 Inmates 0 1 [37] 65 0 1
 Immigrants 0 3 [3840] 77–97 1 [25] 23 4
 Patients with comorbidities 0 0 0 0
 Retrospective studies (n = 25 unique articles; some present data for more than one population and more than one treatment regimen)
 General 0 4 [8992] 82–98 5 [16, 78, 9395] 53–83 9
 Case contacts 0 1 [96] 81 5 [13, 78, 9799] 74–95 6
 Healthcare workers 0 1 [100] 92 4 [78, 94, 101, 102] 47–89 5
 Homeless 0 0 0 0
 PWID 0 1 [103] 56 0 1
 HIV infected 0 1 [104] 67 0 1
 Inmates 0 0 2 [80, 105] 7–90 2
 Immigrants 0 2 [106, 107] 78–84 3 [16, 93, 94] 57–82 5
 Patients with comorbidities 1 [108] 93 1 [109] 82 0 2
Completion rates
 Prospective studies (n = 39 unique articles; some present data for more than one population and more than one treatment regimen)
 General 10 [12, 23, 25, 41, 42, 46, 47, 49, 50, 60] 61–95 10 [12, 18, 24, 25, 41, 42, 46, 47, 50, 57] 46–76 0 13
 Case contacts 2 [51, 52] 71–82 4 [26, 27, 51, 52] 53–73 2 [12, 25] 60–64 6
 Healthcare workers 0 1 [18] 44 0 1
 Homeless 1 [60] 71 2 [18, 30] 25–33 1 [25] 44 4
 PWID 0 4 [31, 32, 56, 58] 38–89 0 4
 HIV infected 6 [36, 44, 48] 62–95 8 [18, 3436, 44, 48, 54, 55] 55–89 0 8
 Inmates 1 [53] 48 3 [37, 53, 62] 4–38 0 3
 Immigrants 2 [43, 59] 72–80 8 [3840, 43, 45, 57] 7–83 2 [12, 25] 61–79 9
 Patients with comorbidities 1 [61] 87 0 0 1
 Retrospective studies (n = 44 unique articles; some present data for more than one population and more than one treatment regimen)
 General 14 [1417, 6567, 78, 79, 8183, 110, 111] 56–93 23 [1416, 6467, 78, 79, 8183, 8992, 112118] 39–96 1 [93] 54 27
 Case contacts 3 [13, 14, 17] 63–69 4 [13, 14, 113, 116] 56–78 5 [78, 82, 97, 98, 119] 48–81 10
 Healthcare workers 0 2 [100, 113] 17–75 3 [15, 78, 101] 40–79 5
 Homeless 1 [120] 44 1 [64] 23 0 2
 PWID 0 1 [103] 55 0 1
 HIV infected 0 2 [14, 104] 55–66 0 2
 Inmates 4 [80, 120] 48–100 2 [80, 121] 23–68 0 3
 Immigrants 4 [14, 16, 17, 122] 60–85 11 [14, 16, 64, 89, 91, 92, 106, 113, 116, 123, 124] 38–86 5 [15, 65, 79, 82, 93] 53–69 18
 Patients with comorbidities 1 [108] 92 1 [125] 75 0 2
  1. HIV human immunodeficiency virus, n number of included studies, N total number of included studies, PWID people who inject drugs