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Table 1 Summary of included studies

From: A systematic review of community based hepatitis C treatment

Study

Year

Country

Design

Intervention

Facility

n

Rx uptake

SVR

n (%)

n (%)

Arora

2011

USA

Prospective cohort study of treatment outcome

Telehealth to support primary care (in community and prison)

Tertiary

146

 

84/146 (58)

Primary total (Prisoners)

261 (106)

 

152/261 (58)

Bruce

2012

USA

Randomised controlled trial of treatment uptake and outcome

Directly observed therapy in OST clinic vs self administered treatment in tertiary clinic

Tertiary

9

4/9 (44)

1/4 (33)

Primary

12

12/12 (100)

6/12 (75)

Chen

2014

Taiwan

Prospective cohort study of treatment outcome

Telecare

Tertiary

150

 

99/150 (66)

Telecare

148

 

102/148 (69)

Gigi

2013

Greece

Retrospective cohort study of treatment uptake

Rx in OST clinic

Tertiary

643 Ab+

276/643 (43)

 

Primary

204 Ab+

17/204 (8)

 

Jou

2013

USA

Retrospective cohort study of treatment outcome

Analysis of data by Rx site

Academic

1905

 

760/1905 (40)

Community

1165

 

455/1165 (39)

Kramer

2010

USA

Retrospective cohort study of treatment uptake

 

Specialist clinic

24,853

3537 (14)

 

Primary Care clinic

1929

251 (13)

 

Kuo

2015

Taiwan

Prospective cohort study of treatment uptake and outcome

Rx in community

Pre intervention

18

4/18 (22)

2/4 (50)

Post intervention

3/16 (19)

3/3 (100)

Moriarty

2001

New Zealand

Observational study of treatment uptake

Rx co-located at NSP site

Tertiary

51

1 (2)

 

Primary

4 (8)

 

Moussalli

2010

France

Observational study of treatment uptake

Rx in OST clinic

Pre intervention

337

2/337 (0.6)

 

Post intervention

85/335 (25)

37/85 (44)

Myers

2011

Canada

Observational study of treatment outcomes

 

Academic

133

 

79/133 (59)

Community

250

 

120/250 (48)

Nazareth

2013

Australia

Retrospective cohort study of treatment outcomes

Telehealth

Tertiary

528

 

311/528 (59)

Telehealth

50

 

36/50 (72)

Niederau

2014

Germany

Prospective cohort study of treatment outcome

Analysis of adherence to guidelines by Rx site

Hospital based

621

 

290/621 (47)

Private practice

3778

 

1744/3778 (46)

Rossaro

2013

USA

Retrospective cohort study of treatment outcomes

Telehealth

Tertiary

40

 

16/37 (43)

Telehealth

40

 

21/38 (55)

  1. Rx treatment, OST opioid substitution therapy, Ab + HCV antibody positive